Quality of life of community-residing persons with dementia based on self-rated and caregiver-rated measures.
Quality of life of community-residing persons with dementia based on self-rated and caregiver-rated measures.
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DOI：
10.1007/s11136-011-0044-z
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发表时间：
2012-10
影响因子：
3.5
通讯作者：
Samus, Quincy M.
中科院分区：
文献类型：
--
作者：
Black, Betty S.;Johnston, Deirdre;Morrison, Ann;Rabins, Peter V.;Lyketsos, Constantine G.;Samus, Quincy M.
关键词：
确定社区居住痴呆患者（PWD）自评和护理者评定的生活质量（QOL）与干预发展的相关性。参与临床试验的254名PWD及其护理人员的横断面数据来自家庭评估。使用生活质量-阿尔茨海默病（QOL- ad）量表测量自评生活质量，使用QOL- ad和阿尔茨海默病相关生活质量（ADRQL）量表测量护理者评定生活质量。多变量模型确定了PWD生活质量的相关因素。自评生活质量与受试者种族、未满足需求、抑郁和总用药相关。照顾者评定的QOL-AD得分与参与者功能、未满足的需求、抑郁和健康问题以及照顾者负担和自评健康显著相关。ADRQL评分的显著相关因素包括神经精神症状严重程度、功能和认知障碍、照顾者负担和抑郁。居住在社区的残疾人士生活质素的相关因素，取决于谁对残疾人士的生活质素进行评分，以及所采用的测量方法。解决健康问题、药物使用和与痴呆症相关的未满足需求，减少功能依赖，治疗PWD患者的神经精神症状，同时减轻照顾者的负担和抑郁，可能会最大限度地提高痴呆症患者的生活质量。
To identify correlates of self-rated and caregiver-rated quality of life (QOL) in community-residing persons with dementia (PWD) for intervention development. Cross-sectional data of 254 PWD and their caregivers participating in a clinical trial were derived from in-home assessments. Self-rated QOL was measured with the Quality of Life-Alzheimer Disease (QOL-AD) scale, and caregiver-rated QOL was measured using the QOL-AD and Alzheimer Disease Related Quality of Life (ADRQL) scales. Multivariate modeling identified correlates of the PWD’ QOL. Self-rated QOL was related significantly to participant race, unmet needs, depression, and total medications. Caregiver-rated QOL-AD scores were significantly associated with participant function, unmet needs, depression, and health problems and with caregiver burden and self-rated health. Significant correlates of ADRQL scores included neuropsychiatric symptom severity, functional and cognitive impairment, and caregiver burden and depression. Correlates of QOL in community-residing PWD depend on who rates the PWD’s QOL and which measure is used. Addressing health problems, medication use, and dementia-related unmet needs, reducing functional dependency, and treating neuropsychiatric symptoms in PWD, while reducing caregiver burden and depression, may maximize QOL in those with dementia.
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