Shared velocity encoding: a method to improve the temporal resolution of phase-contrast velocity measurements.

Shared velocity encoding: a method to improve the temporal resolution of phase-contrast velocity measurements.
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DOI:
10.1002/mrm.23273
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发表时间:
2012-09
影响因子:
3.3
通讯作者:
Simonetti, Orlando P.
Simonetti, Orlando P.
中科院分区:
医学3区
文献类型:
--
作者:
Lin, Hung-Yu;Bender, Jacob A.;Ding, Yu;Chung, Yiu-Cho;Hinton, Alice M.;Pennell, Michael L.;Whitehead, Kevin K.;Raman, Subha V.;Simonetti, Orlando P.

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相位对比磁共振成像(PC-MRI)通常用于测量各种临床应用中的流体和组织速度。PC-MRI方法需要采集额外的数据以实现相位差重建,这使得实时成像成为问题。共享速度编码(SVE),一种旨在提高PC-MRI的有效时间分辨率的方法,在具有分段回波平面读出的实时脉冲序列中实现。在计算机模拟中研究了SVE对峰值速度测量的影响,并在流动体模和志愿者中测量了峰值速度和总流量,并与常规ECG触发的分段k空间相位对比序列作为参考标准进行了比较。计算机模拟表明,SVE的峰值速度误差从8.8%减少到5.6%,减少了36%。在脉动流体模中,峰值速度误差也减少了40%。在体模和志愿者中,在有或没有SVE的情况下测量的体积流量没有显著差异。在志愿者中使用SVE进行的峰值速度测量显示出与参考标准的一致性相关性(0.96)高于非SVE(0.87)。SVE重建的有效时间分辨率的改善对实时PC-MRI峰值速度测量的精度和准确性有积极的影响。
Phase contrast magnetic resonance imaging (PC-MRI) is used routinely to measure fluid and tissue velocity with a variety of clinical applications. PC-MRI methods require acquisition of additional data to enable phase difference reconstruction, making real-time imaging problematic. Shared Velocity Encoding (SVE), a method devised to improve the effective temporal resolution of PC-MRI, was implemented in a real-time pulse sequence with segmented echo planar readout. The effect of SVE on peak velocity measurement was investigated in computer simulation, and peak velocities and total flow were measured in a flow phantom and in volunteers and compared with a conventional ECG-triggered, segmented k-space phase-contrast sequence as a reference standard. Computer simulation showed a 36% reduction in peak velocity error from 8.8% to 5.6% with SVE. A similar reduction of 40% in peak velocity error was shown in a pulsatile flow phantom. In the phantom and volunteers, volume flow did not differ significantly when measured with or without SVE. Peak velocity measurements made in the volunteers using SVE showed a higher concordance correlation (0.96) with the reference standard than non-SVE (0.87). The improvement in effective temporal resolution with SVE reconstruction has a positive impact on the precision and accuracy of real-time PC-MRI peak velocity measurements.
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