Effects of pelvic endometriosis and adenomyosis on ciliary beat frequency and muscular contractions in the human fallopian tube.
Effects of pelvic endometriosis and adenomyosis on ciliary beat frequency and muscular contractions in the human fallopian tube.
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盆腔子宫内膜异位症和子宫腺肌病对输卵管纤毛跳动频率和肌肉收缩的影响
DOI：
10.1186/s12958-018-0361-y
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发表时间：
2018-05-12
期刊：
影响因子：
--
通讯作者：
Zhang J
中科院分区：
文献类型：
--
作者：
Xia W;Zhang D;Ouyang J;Liang Y;Zhang H;Huang Z;Liang G;Zhu Q;Guan X;Zhang J
盆腔子宫内膜异位症（EM）和子宫腺肌症（AM）对输卵管的影响不同。本研究旨在评估患有盆腔EM或AM的女性输卵管的运输能力。方法选取20例子宫平滑肌瘤患者（对照组）、20例无盆腔EM患者（AM组）和35例无AM盆腔EM患者（EM组）。EM病例进一步分为管状EM和非管状EM亚组。测定纤毛搏动频率（CBF）、纤毛细胞百分比、平滑肌收缩。结果EM组壶腹scbfs明显低于对照组和AM组；输卵管性EM患者壶腹和峡部cbf明显低于对照组和非输卵管性EM亚组。在壶腹和峡段，EM患者纤毛细胞的百分比均显著低于AM和对照组；管状EM亚组明显低于对照组和非管状EM亚组。EM患者纵向肌肉收缩力的幅重比显著低于对照组；输卵管性EM病例的数值明显低于对照组和非输卵管性EM亚组。EM组纵向肌和圆形肌的收缩频率均显著低于对照组和AM组；输卵管性EM病例的数值明显低于对照组和非输卵管性EM亚组。结论有管状EM的EM对输卵管运输功能有不同程度的损害，而无管状EM的EM和AM对输卵管功能没有影响。
BackgroundPelvic endometriosis (EM) and adenomyosis (AM) have different effects on the fallopian tube. This study aimed to assess the transport capability of the fallopian tube in women with pelvic EM or AM.MethodsTwenty women with uterine leiomyoma (control group), 20 with adenomyosis without pelvic EM (AM group) and 35 with pelvic EM without AM (EM group) were included. EM cases were further divided into the tubal EM and non-tubal EM subgroups. Ciliary beat frequency (CBF), percentage of ciliated cells, and smooth muscle contraction were measured.ResultsCBFs of the ampulla in EM cases were significantly lower than those of control and AM cases; CBFs of the ampulla and isthmus in tubal EM cases were significantly lower than those of the control group and non-tubal EM subgroup. In both the ampulla and isthmus segment, percentages of ciliated cells in EM patients were significantly lower than those of AM and control patients; the tubal EM subgroup showed significantly lower values than the control group and non-tubal EM subgroup. Amplitude-to-weight ratios of longitudinal muscular contractility in EM cases were significantly lower than control values; tubal EM cases showed significantly lower values than controls and the non-tubal EM subgroup. Contraction frequencies in EM cases were significantly lower than those of control and AM cases, in both longitudinal and circular muscles; tubal EM cases showed significantly lower values than controls and the non-tubal EM subgroup.ConclusionEM with tubal EM damaged transport function of the fallopian tube, to varying degrees, whereas tubal function in EM without tubal EM and in AM is not altered.
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DOI：
10.1111/j.1471-0528.2005.00676.x
发表时间：
2005-10-01
影响因子：
5.8
作者：
Kissler, S;Hamscho, N;Kaufmann, M
通讯作者：
Kaufmann, M
影响因子：
6.7
作者：
Papathanasiou, A.;Djahanbakhch, O.;Lyons, R. A.
通讯作者：
Lyons, R. A.
影响因子：
6.1
作者：
Raidt, Johanna;Werner, Claudius;Omran, Heymut
通讯作者：
Omran, Heymut
DOI：
10.1196/annals.1389.036
发表时间：
2007-01-01
期刊：
REPRODUCTIVE BIOMECHANICS
影响因子：
--
作者：
Kissler, Stefan;Zangos, Stephan;Kaufmann, Manfred
通讯作者：
Kaufmann, Manfred
影响因子：
3.6
作者：
Chen, Shuai;Einspanier, Ralf;Schoen, Jennifer
通讯作者：
Schoen, Jennifer