Optofluidic Flow-Through Biosensor Sensitivity - Model and Experiment.
Optofluidic Flow-Through Biosensor Sensitivity - Model and Experiment.
复制标题
光流体流通生物传感器灵敏度-模型和实验。
DOI:
10.1109/jlt.2021.3061872
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发表时间:
2021-05-15
期刊:
影响因子:
--
通讯作者:
Hawkins AR
中科院分区:
文献类型:
--
作者:
Wright JG Jr;Amin MN;Meena GG;Schmidt H;Hawkins AR
We present a model and simulation for predicting the detected signal of a fluorescence-based optical biosensor built from optofluidic waveguides. Typical applications include flow experiments to determine pathogen concentrations in a biological sample after tagging relevant DNA or RNA sequences. An overview of the biosensor geometry and fabrication processes is presented. The basis for the predictive model is also outlined. The model is then compared to experimental results for three different biosensor designs. The model is shown to have similar signal statistics as physical tests, illustrating utility as a pre-fabrication design tool and as a predictor of detection sensitivity.
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影响因子:
3.8
作者:
Meena, G. G.;Wall, T. A.;Schmidt, H.
通讯作者:
Schmidt, H.
影响因子:
12.6
作者:
Du K;Cai H;Park M;Wall TA;Stott MA;Alfson KJ;Griffiths A;Carrion R;Patterson JL;Hawkins AR;Schmidt H;Mathies RA
通讯作者:
Mathies RA
DOI:
10.1109/jstqe.2018.2854574
发表时间:
2019-01-01
影响因子:
4.9
作者:
Black, Jennifer A.;Hamilton, Erik;Schmidt, Holger
通讯作者:
Schmidt, Holger
影响因子:
4
作者:
DUGUAY, MA;KOKUBUN, Y;PFEIFFER, L
通讯作者:
PFEIFFER, L
DOI:
10.1016/0735-1933(94)90046-9
发表时间:
1994-07-01
影响因子:
7
作者:
SPIGA, M;MORINI, GL
通讯作者:
MORINI, GL