AnnoTrack--a tracking system for genome annotation.
AnnoTrack--a tracking system for genome annotation.
复制标题
DOI：
10.1186/1471-2164-11-538
复制
发表时间：
2010-10-05
期刊：
影响因子：
4.4
通讯作者：
Hubbard T
中科院分区：
文献类型：
--
作者：
Kokocinski F;Harrow J;Hubbard T
随着越来越多的模式生物的基因组序列被测定，生物学家群体对更好的工具的需求日益增长，以促进统一的基因组注释工作。通常这一过程涉及该领域的众多专家以及使用来自不同来源的数据作为证据。这种协作注释项目需要专门的软件解决方案来进行高效的数据跟踪和处理。
作为ENCODE项目（DNA元件百科全书）扩大阶段的一部分，GENCODE项目的目标是为人类基因组生成一个高度精确的基于证据的参考基因注释。AnnoTrack软件系统是为辅助这一工作而开发的。它整合了来自多个分布式来源的数据，突出显示冲突，并促进在基因组注释过程中快速识别、确定优先级以及解决问题。
AnnoTrack在过去一年中一直在使用，并已被证明是大规模基因组注释的一个非常有价值的工具。它被设计为可与标准生物信息学组件（如DAS服务器和Ensembl数据库）对接，对于不同的基因组项目很容易设置和配置。源代码可在http://annotrack.sanger.ac.uk获取。
As genome sequences are determined for increasing numbers of model organisms, demand has grown for better tools to facilitate unified genome annotation efforts by communities of biologists. Typically this process involves numerous experts from the field and the use of data from dispersed sources as evidence. This kind of collaborative annotation project requires specialized software solutions for efficient data tracking and processing. As part of the scale-up phase of the ENCODE project (Encyclopedia of DNA Elements), the aim of the GENCODE project is to produce a highly accurate evidence-based reference gene annotation for the human genome. The AnnoTrack software system was developed to aid this effort. It integrates data from multiple distributed sources, highlights conflicts and facilitates the quick identification, prioritisation and resolution of problems during the process of genome annotation. AnnoTrack has been in use for the last year and has proven a very valuable tool for large-scale genome annotation. Designed to interface with standard bioinformatics components, such as DAS servers and Ensembl databases, it is easy to setup and configure for different genome projects. The source code is available at http://annotrack.sanger.ac.uk.
登录
查看更多内容
影响因子：
7
作者：
Pruitt, Kim D.;Harrow, Jennifer;Lipman, David
通讯作者：
Lipman, David
影响因子：
12.3
作者：
Harrow J;Denoeud F;Frankish A;Reymond A;Chen CK;Chrast J;Lagarde J;Gilbert JG;Storey R;Swarbreck D;Rossier C;Ucla C;Hubbard T;Antonarakis SE;Guigo R
通讯作者：
Guigo R
影响因子：
3
作者：
Jenkinson, Andrew M.;Albrecht, Mario;Prlic, Andreas
通讯作者：
Prlic, Andreas
影响因子：
14.9
作者：
Flicek P;Aken BL;Ballester B;Beal K;Bragin E;Brent S;Chen Y;Clapham P;Coates G;Fairley S;Fitzgerald S;Fernandez-Banet J;Gordon L;Gräf S;Haider S;Hammond M;Howe K;Jenkinson A;Johnson N;Kähäri A;Keefe D;Keenan S;Kinsella R;Kokocinski F;Koscielny G;Kulesha E;Lawson D;Longden I;Massingham T;McLaren W;Megy K;Overduin B;Pritchard B;Rios D;Ruffier M;Schuster M;Slater G;Smedley D;Spudich G;Tang YA;Trevanion S;Vilella A;Vogel J;White S;Wilder SP;Zadissa A;Birney E;Cunningham F;Dunham I;Durbin R;Fernández-Suarez XM;Herrero J;Hubbard TJ;Parker A;Proctor G;Smith J;Searle SM
通讯作者：
Searle SM