Resveratrol oligomers for the prevention and treatment of cancers.
Resveratrol oligomers for the prevention and treatment of cancers.
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用于预防和治疗癌症的白藜芦醇低聚物
DOI：
10.1155/2014/765832
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发表时间：
2014
影响因子：
--
通讯作者：
Shi Z
中科院分区：
文献类型：
--
作者：
Xue YQ;Di JM;Luo Y;Cheng KJ;Wei X;Shi Z
白藜芦醇(3，4‘，5-三羟基二苯乙烯)是从葡萄等植物中分离得到的一种天然植物保健素，对人体健康有重要作用，具有广泛的抗氧化、抗炎、抗癌等生物活性。除了白藜芦醇，科学家们还关注白藜芦醇低聚物，白藜芦醇的衍生物，其特征是聚合2到8个，甚至更多的白藜芦醇单元，是低聚二苯乙烯中最大的一类。白藜芦醇低聚物具有多种有益的性质，其中一些在活性、稳定性和选择性方面优于白藜芦醇。其复杂的结构和多样的生物活性在药物研究和开发中具有重要的意义，并有望作为癌症预防和治疗药物。本文对白藜芦醇低聚物的预防或抗癌性能进行了综述。
Resveratrol (3,4′,5-trihydroxystilbene) is a naturally derived phytoalexin stilbene isolated from grapes and other plants, playing an important role in human health and is well known for its extensive bioactivities, such as antioxidation, anti-inflammatory, anticancer. In addition to resveratrol, scientists also pay attention to resveratrol oligomers, derivatives of resveratrol, which are characterized by the polymerization of two to eight, or even more resveratrol units, and are the largest group of oligomeric stilbenes. Resveratrol oligomers have multiple beneficial properties, of which some are superior in activity, stability, and selectivity compared with resveratrol. The complicated structures and diverse biological activities are of significant interest for drug research and development and may provide promising prospects as cancer preventive and therapeutical agents. This review presents an overview on preventive or anticancer properties of resveratrol oligomers.
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影响因子：
3.7
作者：
Hofer, T;Badouard, C;Cotgreave, IA
通讯作者：
Cotgreave, IA
DOI：
10.1093/jnci/84.24.1887
发表时间：
1992-12-16
期刊：
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子：
--
作者：
HOWE, GR;BENITO, E;ZHENG, S
通讯作者：
ZHENG, S
影响因子：
6.1
作者：
Gonzalez-Sarrias, Antonio;Gromek, Samantha;Henry, Geneive E.
通讯作者：
Henry, Geneive E.
DOI：
10.1111/j.1749-6632.2002.tb02918.x
发表时间：
2002-01-01
期刊：
ALCOHOL AND WINE IN HEALTH AND DISEASE
影响因子：
--
作者：
Bhat, KPL;Pezzuto, JM
通讯作者：
Pezzuto, JM
影响因子：
2
作者：
Ito, T;Akao, Y;Nozawa, Y
通讯作者：
Nozawa, Y