Visualize: a free and open source multifunction tool for proteomics data analysis.

Visualize: a free and open source multifunction tool for proteomics data analysis.
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DOI:
10.1002/pmic.201000556
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发表时间:
2011-03
期刊:
影响因子:
3.4
通讯作者:
Greene, Andrew S.
Greene, Andrew S.
中科院分区:
生物学3区
文献类型:
--
作者:
Halligan, Brian D.;Greene, Andrew S.

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高通量蛋白质组学领域的一个主要挑战是将产生的大量实验数据转化为生物学知识。通常,蛋白质组学实验涉及多个数据集的组合和比较,以及这些组合结果的分析和注释。虽然有一些商业应用程序提供了其中的一些功能,但仍然需要一个免费的、开源的、多功能的工具来进行高级蛋白质组学数据分析。我们开发了可视化程序,为用户提供可视化,分析和注释蛋白质组学数据的能力;合并多个运行的数据,并量化单个运行和组合数据集之间的差异。visualview是根据GNU GPL许可的,可以从http://proteomics.mcw.edu/visualize下载。它可以作为Windows和Mac OS X平台上编译的基于客户机的可执行文件以及PERL源代码获得。
A major challenge in the field of high-throughput proteomics is the conversion of the large volume of experimental data that is generated into biological knowledge. Typically, proteomics experiments involve the combination and comparison of multiple data sets and the analysis and annotation of these combined results. Although there are some commercial applications that provide some of these functions, there is a need for a free, open source, multifunction tool for advanced proteomics data analysis. We have developed the Visualize program that provides users with the abilities to visualize, analyze, and annotate proteomics data; combine data from multiple runs, and quantitate differences between individual runs and combined data sets. Visualize is licensed under GNU GPL and can be downloaded from http://proteomics.mcw.edu/visualize. It is available as compiled client-based executable files for both Windows and Mac OS X platforms as well as PERL source code.
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