Treatment-related optimistic beliefs and risk of HIV transmission: a review of recent findings (2009-2012) in an era of treatment as prevention.

Treatment-related optimistic beliefs and risk of HIV transmission: a review of recent findings (2009-2012) in an era of treatment as prevention.
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DOI:
10.1007/s11904-012-0144-6
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发表时间:
2013-03
影响因子:
4.6
通讯作者:
Chen, Yiyun
Chen, Yiyun
中科院分区:
医学2区
文献类型:
--
作者:
Chen, Yiyun

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最近临床试验的成功为艾滋病毒治疗预防(TasP)带来了光明的前景,这凸显了需要努力避免对抗逆转录病毒治疗(ART)过于乐观。人们最关心的是,这种乐观的信念可能会加剧危险行为,以抵消抗逆转录病毒治疗对降低艾滋病毒总体传播率的保护作用。当前的审查旨在提供与治疗相关的乐观信念对艾滋病毒传播风险的潜在影响的最新看法。该综述在过去 4 年中总共发表了 14 项研究,这些研究探讨了与治疗相关的乐观信念在改变人们采取危险性行为方面的作用。定量研究的结果在很大程度上支持乐观信念与艾滋病毒传播风险之间的关联。定性研究的结果发现了数字关联下隐藏的更多信息,并指出需要对乐观信念与艾滋病毒传播风险之间的关系进行更严格和全面的检查。确定了当前文献中的差距,并为未来的研究提供了建议。
The promising outlook for HIV treatment as prevention (TasP) offered by the recent success in clinical trials has highlighted the need for effort against over-optimism toward anti-retroviral therapy (ART). It has been of a central concern that such optimistic beliefs may fuel an increase in risk behaviors to counter the protective effect of ART on reducing overall transmissibility of HIV. The current review was conducted to provide an updated look at the potential impact of treatment-related optimistic beliefs on the risk of HIV transmission. The review yielded a total of 14 studies published during the past 4 years that have examined the role of treatment-related optimistic beliefs in changing people’s adoption of sexual risk behaviors. Findings from quantitative studies were largely in support of an association between optimistic beliefs and risk of HIV transmission. Results from qualitative studies discovered additional information concealed under the numerical associations, and pointed to the need of more rigorous and comprehensive examination of the relationship between optimistic beliefs and HIV transmission risk. Gaps in the current literature were identified and suggestions for future research were provided.
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