Inter-individual performance differences in younger and older adults differentially relate to amplitude modulations and phase stability of oscillations controlling working memory contents

Inter-individual performance differences in younger and older adults differentially relate to amplitude modulations and phase stability of oscillations controlling working memory contents
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年轻人和老年人的个体间表现差异与控制工作记忆内容的振荡的振幅调制和相位稳定性有不同的关系

DOI:
10.1016/j.neuroimage.2011.11.071
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发表时间:
2012
期刊:
影响因子:
5.7
通讯作者:
Klimesch
Klimesch
中科院分区:
医学1区
文献类型:
--
作者:
Werkle-Bergner;Freunberger;Sander;Lindenberger;Klimesch

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相关信息的有效编码和不相关信息的抑制会影响工作记忆(WM)的表现,而工作记忆的表现是有限的,并且在成年后会下降。提示斯滕伯格 WM 任务和脑电图记录 (EEG) 用于研究年轻人和老年人对待记住 (REM) 和不记住 (NREM) 刺激的编码和控制操作。年轻人和老年人在最终的认知记忆测试中选择性地记住了快速眼动项目。在刺激处理的早期阶段,年轻人和老年人中 REM 项目的试验间阶段稳定性高于 NREM 项目,这可能反映了 REM 项目的优先编码。在后期阶段,NREM 的 α/β 频率范围内振荡的振荡功率高于 REM,这可能反映了对与任务无关的信息的自上而下的抑制。早期稳定性选择性地与年轻人和高功能老年人的工作记忆表现相关。这项研究的结果揭示了低水平特征绑定和策略控制成分对 WM 成人年龄差异的不同贡献,并表明具有更多类似年轻人的处理动态的老年人往往会取得更高水平的表现。
Efficient encoding of relevant information and suppression of irrelevant information influence working memory (WM) performance, which is limited and declines in adulthood. A cued Sternberg WM task and electroencephalographic recordings (EEG) were used to investigate encoding and control operations in response to to-be-remembered (REM) and not-to-be-remembered (NREM) stimuli in younger and older adults. Younger and older adults selectively remembered REM items in a final recognition memory test. During early stages of stimulus processing, inter-trial phase stability was higher for REM than for NREM items in younger and older adults, presumably reflecting preferential encoding of REM items. At later stages, the oscillatory power of oscillations in the alpha/beta frequency range was higher for NREM than for REM, presumably reflecting the inhibitory top–down suppression of task-irrelevant information. Early phase stability was selectively related to working memory performance in younger adults and high-functioning older adults. The results of this study reveal the differential contributions of low-level feature binding and strategic control components to adult age differences in WM, and show that older adults with more youth-like processing dynamics tend to achieve higher levels of performance.
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