Overview of Salvia miltiorrhiza as a Potential Therapeutic Agent for Various Diseases: An Update on Efficacy and Mechanisms of Action.
Overview of Salvia miltiorrhiza as a Potential Therapeutic Agent for Various Diseases: An Update on Efficacy and Mechanisms of Action.
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DOI：
10.3390/antiox9090857
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发表时间：
2020-09-13
期刊：
影响因子：
--
通讯作者：
Kim B
中科院分区：
文献类型：
--
作者：
Jung I;Kim H;Moon S;Lee H;Kim B
丹参（Salvia miltiorrhiza Bunge，S.丹参）是一种草药，在包括韩国在内的东亚已被用于治疗各种疾病，如心血管和脑血管疾病。考虑到其作为多种疾病的治疗剂的广泛用途，有必要回顾其治疗益处及其机制的先前研究。因此，我们在PubMed和PubMed Central中检索了报告其对某些疾病组（包括癌症、心血管、肝脏和神经系统疾病）治疗效果的文章。本文就S.丹参，包括炎症，纤维化，氧化应激和细胞凋亡。对S.本文所讨论的丹参支持S.丹参提取物对多种疾病的治疗作用，但还需要进一步研究其治疗作用的多种机制。
Salvia miltiorrhiza Bunge (S. miltiorrhiza) is a medicinal herb that has been used for the treatment for various diseases such as cardiovascular and cerebrovascular diseases in East Asia including Korea. Considering its extensive usage as a therapeutic agent for multiple diseases, there is a need to review previous research regarding its therapeutic benefits and their mechanisms. Therefore, we searched PubMed and PubMed Central for articles reporting its therapeutic effects on certain disease groups including cancers, cardiovascular, liver, and nervous system diseases. This review provides an overview of therapeutic benefits and targets of S. miltiorrhiza, including inflammation, fibrosis, oxidative stress, and apoptosis. The findings on multi-functional properties of S. miltiorrhiza discussed in this article support the efficacy of S. miltiorrhiza extract on various diseases, but also call for further research on the multiple mechanisms that mediate its therapeutic effects.
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20.1
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