Porcine epidemic diarrhoea virus: a comprehensive review of molecular epidemiology, diagnosis, and vaccines.

Porcine epidemic diarrhoea virus: a comprehensive review of molecular epidemiology, diagnosis, and vaccines.
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猪流行腹泻病毒:分子流行病学,诊断和疫苗的全面回顾。

DOI:
10.1007/s11262-012-0713-1
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发表时间:
2012-04
期刊:
影响因子:
1.6
通讯作者:
Park B
Park B
中科院分区:
医学4区
文献类型:
--
作者:
Song D;Park B

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猪流行性腹泻病毒(PEDV)是冠状病毒科的一个成员,引起猪的急性腹泻和脱水。虽然它首先在欧洲被发现,但在许多亚洲国家,包括韩国,中国,日本,菲律宾和泰国,它已经成为越来越多的问题。PEDV的经济影响是巨大的,因为它导致新生仔猪的显著发病率和死亡率,并且与疫苗接种和消毒相关的成本增加有关。最近,在理解PEDV的分子流行病学方面取得了进展,从而导致新疫苗的开发。在本综述中,我们首先描述了PEDV的分子和遗传特征。然后,我们讨论了它的分子流行病学和诊断,什么疫苗是可用的,以及如何PEDV可以治疗。
The porcine epidemic diarrhoea virus (PEDV), a member of the Coronaviridae family, causes acute diarrhoea and dehydration in pigs. Although it was first identified in Europe, it has become increasingly problematic in many Asian countries, including Korea, China, Japan, the Philippines, and Thailand. The economic impacts of the PEDV are substantial, given that it results in significant morbidity and mortality in neonatal piglets and is associated with increased costs related to vaccination and disinfection. Recently, progress has been made in understanding the molecular epidemiology of PEDV, thereby leading to the development of new vaccines. In the current review, we first describe the molecular and genetic characteristics of the PEDV. Then we discuss its molecular epidemiology and diagnosis, what vaccines are available, and how PEDV can be treated.
DOI: 10.1016/s0166-0934(02)00063-0
发表时间: 2002-08
影响因子: 3.1
作者:
de Arriba ML;Carvajal A;Pozo J;Rubio P
通讯作者: Rubio P
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发表时间: 2002-01-01
影响因子: 1.8
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