Diagnosing autism spectrum disorders in adults: the use of Autism Diagnostic Observation Schedule (ADOS) module 4.

Diagnosing autism spectrum disorders in adults: the use of Autism Diagnostic Observation Schedule (ADOS) module 4.
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DOI:
10.1007/s10803-010-1157-x
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发表时间:
2011-09
影响因子:
3.9
通讯作者:
de Bildt, Annelies
de Bildt, Annelies
中科院分区:
心理学3区
文献类型:
--
作者:
Bastiaansen, Jojanneke A.;Meffert, Harma;Hein, Simone;Huizinga, Petra;Ketelaars, Cees;Pijnenborg, Marieke;Bartels, Arnold;Minderaa, Ruud;Keysers, Christian;de Bildt, Annelies

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自闭症诊断观察计划(ADOS)模块4在一个独立的患有自闭症谱系障碍(ASD)的高功能成年男性样本中进行了研究,并与三个特定的诊断组进行了比较:精神分裂症、精神病和典型发育。ADOS模块4是一种可靠的仪器,具有良好的预测价值。它可以充分区分ASD与精神病和典型发育,但对于精神分裂症,由于自闭症和阴性症状之间的行为重叠,它的特异性较低。然而,这些小组在一些核心项目上存在分歧,探索性分析表明,对算法的修订符合Gotham等人的要求。(J孤独症Dev Disord 37:613-627,)可能有助于区分自闭症和精神分裂症。
Autism Diagnostic Observation Schedule (ADOS) module 4 was investigated in an independent sample of high-functioning adult males with an autism spectrum disorder (ASD) compared to three specific diagnostic groups: schizophrenia, psychopathy, and typical development. ADOS module 4 proves to be a reliable instrument with good predictive value. It can adequately discriminate ASD from psychopathy and typical development, but is less specific with respect to schizophrenia due to behavioral overlap between autistic and negative symptoms. However, these groups differ on some core items and explorative analyses indicate that a revision of the algorithm in line with Gotham et al. (J Autism Dev Disord 37: 613–627,) could be beneficial for discriminating ASD from schizophrenia.
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