Burden, determinants, consequences and care of multimorbidity in rural and urbanising Telangana, India: protocol for a mixed-methods study within the APCAPS cohort.
Burden, determinants, consequences and care of multimorbidity in rural and urbanising Telangana, India: protocol for a mixed-methods study within the APCAPS cohort.
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DOI：
10.1136/bmjopen-2023-073897
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发表时间：
2023-11-27
期刊：
影响因子：
2.9
通讯作者：
中科院分区：
文献类型：
--
作者：
流行病学和人口结构的转变正在导致全世界多发病（两种或两种以上慢性病同时发生）的负担不断增加。在印度农村和城市化的负担，决定因素，后果和护理的多morphine的证据是有限的，部分原因是缺乏纵向和客观衡量的慢性健康状况的数据。我们将在安得拉邦儿童和家长研究（APCAPS）队列中进行一项混合方法研究，以开发数据资源，用于了解印度农村和城市化中多发性骨髓瘤的流行病学，并制定干预措施，以改善多发性骨髓瘤的预防和护理。我们的目标是招募2100名年龄在45岁以上的APCAPS队列成员，他们在之前的队列随访（2010-2012）中收集了临床和生活方式数据。我们将采用自我报告的临床诊断、基于健康的问卷、体检和生化分析相结合的方法，筛查当地流行的非传染性、传染性和精神健康状况，以及认知障碍、残疾和虚弱。我们将对不同多发病人群、他们的非正式护理人员和当地医疗服务提供者进行深入访谈。未经识别的数据将提供给外部研究人员。该研究已获得印度海得拉巴国家营养研究所和印度公共卫生研究所以及英国伦敦卫生和热带医学院伦理委员会的批准。元数据和数据收集工具将在亚太农业政策研究中心网站上公布，同时公布亚太农业政策研究中心现有数据和数据访问程序的详细情况（www.lshtm.ac.uk/research/centres-projects-groups/apcaps）。
The epidemiological and demographic transitions are leading to a rising burden of multimorbidity (co-occurrence of two or more chronic conditions) worldwide. Evidence on the burden, determinants, consequences and care of multimorbidity in rural and urbanising India is limited, partly due to a lack of longitudinal and objectively measured data on chronic health conditions. We will conduct a mixed-methods study nested in the prospective Andhra Pradesh Children and Parents’ Study (APCAPS) cohort to develop a data resource for understanding the epidemiology of multimorbidity in rural and urbanising India and developing interventions to improve the prevention and care of multimorbidity. We aim to recruit 2100 APCAPS cohort members aged 45+ who have clinical and lifestyle data collected during a previous cohort follow-up (2010–2012). We will screen for locally prevalent non-communicable, infectious and mental health conditions, alongside cognitive impairments, disabilities and frailty, using a combination of self-reported clinical diagnosis, symptom-based questionnaires, physical examinations and biochemical assays. We will conduct in-depth interviews with people with varying multimorbidity clusters, their informal carers and local healthcare providers. Deidentified data will be made available to external researchers. The study has received approval from the ethics committees of the National Institute of Nutrition and Indian Institute of Public Health Hyderabad, India and the London School of Hygiene and Tropical Medicine, UK. Meta-data and data collection instruments will be published on the APCAPS website alongside details of existing APCAPS data and the data access process (www.lshtm.ac.uk/research/centres-projects-groups/apcaps).
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