Age-related changes in mechanical properties of semitendinosus tendon used for anterior cruciate ligament reconstruction.
Age-related changes in mechanical properties of semitendinosus tendon used for anterior cruciate ligament reconstruction.
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DOI：
10.1186/s13018-022-03395-9
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发表时间：
2022-11-19
影响因子：
2.6
通讯作者：
Takazawa, Yuji
中科院分区：
文献类型：
--
作者：
Akazawa, Takuto;Miyamoto, Naokazu;Nishio, Hirofumi;Miyamoto-Mikami, Eri;Kinoshita, Mayuko;Kobayashi, Yohei;Nagao, Masashi;Takazawa, Yuji
腘绳肌腱是前交叉韧带（ACL）重建中常用的自体移植物。然而，越来越多的证据表明，在年轻患者中，自体腘绳肌腱移植具有很高的翻修和残余不稳定风险。为了阐明年轻患者腘绳肌腱自体移植术重建前交叉韧带效果较差的原因，我们研究了杨氏模量和用于前交叉韧带重建的半腱肌腱在循环载荷下松弛的程度。26例男性患者（年龄17-53岁）计划行自体半腱肌腱重建前交叉韧带手术。采集的半腱肌腱远端部分未用于构建自体移植物，用于循环拉伸测试以计算杨氏模量和松弛程度（即松弛长度的增加）。Spearman相关分析显示，半腱肌腱杨氏模量与患者年龄呈正相关（ρ = 0.559, P = 0.003）。相反，肌腱松弛的程度与患者的年龄无关。我们证明了半腱肌腱的杨氏模量随着年龄的增长而增加，这表明用于前交叉韧带重建的半腱肌腱在年轻患者中是顺应性的。
Hamstring tendons are a popular choice for autografts in anterior cruciate ligament (ACL) reconstruction. However, there is increasing evidence that hamstring tendon autografts carry a high risk of revision and residual instability in young patients. To elucidate the reasons for the inferior outcome of the reconstructed ACL with hamstring tendon autografts in young patients, we investigated the Young’s modulus and the extent of cyclic loading-induced slackening of the semitendinosus tendon used for ACL reconstruction across a broad range of ages. Twenty-six male patients (aged 17–53 years), who were scheduled for ACL reconstruction surgery using the semitendinosus tendon autograft, participated in this study. The distal portion of the harvested semitendinosus tendon, which was not used to construct the autograft, was used for cyclic tensile testing to calculate the Young’s modulus and the extent of slackening (i.e., increase in slack length). Spearman correlation analysis revealed that the Young’s modulus of the semitendinosus tendon was positively correlated with the patient’s age (ρ = 0.559, P = 0.003). In contrast, the extent of tendon slackening did not correlate with the patient’s age. We demonstrated that the Young’s modulus of the semitendinosus tendon increases with age, indicating that the semitendinosus tendon used for ACL reconstruction is compliant in young patients.
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影响因子：
3.8
作者：
Guillard, Claude;Lintz, Francois;Robert, Henri
通讯作者：
Robert, Henri
影响因子：
4.8
作者：
Hansen, Philip;Kovanen, Vuokko;Magnusson, S. Peter
通讯作者：
Magnusson, S. Peter
DOI：
10.1016/j.clinbiomech.2009.12.007
发表时间：
2010-05
期刊：
Clinical biomechanics (Bristol, Avon)
影响因子：
--
作者：
Abramowitch SD;Zhang X;Curran M;Kilger R
通讯作者：
Kilger R
DOI：
10.1115/1.2898732
发表时间：
2008-04-01
影响因子：
1.7
作者：
Goh, K. L.;Holmes, D. F.;Wess, T. J.
通讯作者：
Wess, T. J.
DOI：
10.1016/j.arthro.2011.11.024
发表时间：
2012-04-01
影响因子：
4.7
作者：
Magnussen, Robert A.;Lawrence, J. Todd R.;Garrett, William E.
通讯作者：
Garrett, William E.