Visual Control of Walking Speed in Drosophila.

Visual Control of Walking Speed in Drosophila.
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DOI:
10.1016/j.neuron.2018.10.028
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发表时间:
2018-12-19
期刊:
影响因子:
16.2
通讯作者:
Clark DA
Clark DA
中科院分区:
医学1区
文献类型:
--
作者:
Creamer MS;Mano O;Clark DA

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动物的自我运动会产生穿过视网膜的光流,它可以利用这种视觉信号来调节自己在世界中的方向和速度。虽然方向控制在果蝇和其他昆虫中得到了广泛的研究,但对调节翻译速度的视觉线索和电路知之甚少。在这里,我们表明,苍蝇调节步行速度的算法,是调整到视觉运动的速度,使他们放慢时,视觉物体附近。这种调节并不强烈依赖于空间结构或视觉刺激的方向,使其在算法上不同于控制方向的经典计算。尽管算法不同,但调节行走速度的视觉回路与调节方向的视觉回路重叠。总之,我们的研究结果表明,步行速度是由一个分层计算,结合多个运动检测器与不同的调谐控制。在导航过程中,动物调节旋转和平移。Creamer等人研究了视觉运动线索如何调节果蝇的行走速度。他们发现,方向和步行速度通过具有不同调谐的算法来稳定,但使用重叠的电路。
An animal’s self-motion generates optic flow across its retina, and it can use this visual signal to regulate its orientation and speed through the world. While orientation control has been studied extensively in Drosophila and other insects, much less is known about the visual cues and circuits that regulate translational speed. Here we show that flies regulate walking speed with an algorithm that is tuned to the speed of visual motion, causing them to slow when visual objects are nearby. This regulation does not depend strongly on the spatial structure or the direction of visual stimuli, making it algorithmically distinct from the classical computation that controls orientation. Despite the different algorithms, the visual circuits that regulate walking speed overlap with those that regulate orientation. Taken together, our findings suggest that walking speed is controlled by a hierarchical computation that combines multiple motion detectors with distinct tunings. During navigation, animals regulate both rotation and translation. Creamer et al. investigated how visual motion cues regulate walking speed in Drosophila. They found that orientation and walking speed are stabilized by algorithms with distinct tunings but employ overlapping circuitry.
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