Interactions between life expectancy and the incidence and mortality rates of cancer in China: a population-based cluster analysis.
Interactions between life expectancy and the incidence and mortality rates of cancer in China: a population-based cluster analysis.
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DOI：
10.1186/s40880-018-0308-x
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发表时间：
2018-07-03
期刊：
影响因子：
--
通讯作者：
Chen W
中科院分区：
文献类型：
--
作者：
Gu X;Zheng R;Xia C;Zeng H;Zhang S;Zou X;Yang Z;Li H;Chen W
癌症和预期寿命之间的关系在发达国家和发展中国家都得到了很好的证实。中国是一个幅员辽阔的国家，在人口结构和医疗保健方面存在显著的地理差异，因此为分析预期寿命与癌症发病率和死亡率之间的复杂关系提供了独特的机会。癌症数据是从2013年国家中央癌症登记中心提取的总计255个单位(市或县)的数据。单位一级的预期寿命数据来自国家疾病控制和预防中心。采用线性回归分析方法分析预期寿命与癌症粗发病率和死亡率的关系。在另一项分析中，预期寿命被评为低(<； 76岁)、中(76-80岁)或高(>； 80岁)。总体而言，癌症发病率和死亡率与预期寿命呈正相关(R值分别为0.37和0.50，P <； 为0.001)。在肺癌、结直肠癌、前列腺癌、膀胱癌和胰腺癌以及男性淋巴瘤(R0.36-0.58，P <； 0.001)、女性肺癌、乳腺癌、结直肠癌、甲状腺、子宫和卵巢癌(R0.18-0.51，P <； 0.001)中相关性显著。我们未能观察到上消化道癌症与预期寿命之间的联系。低、中、高预期寿命水平的市县分别为110个、101个和44个。年龄标准化癌症发病率最高的是预期寿命水平较高的地区(192.83/100,000)。年龄标化死亡率最高的是预期寿命最低的地区(118.44/100,000)。胃癌、肝癌和食道癌是中低预期寿命地区的主要癌症类型。相比之下，预期寿命高的地区结直肠癌、女性乳腺癌和男性前列腺癌的发病率和死亡率都很高。在中国，较长的预期寿命与较高的总体癌症发病率和死亡率相关。癌症模式在预期寿命水平不同的地区也有很大差异。制定预防和治疗癌症的战略时，必须考虑预期寿命水平。
The relationship between cancer and life expectancy is well established in both developed and developing countries. China is a vast country with significant geographical differences in population structure and healthcare, and thus provides a unique opportunity to analyze the complex relationship between life expectancy and cancer incidence and mortality rates. Cancer data were extracted for a total of 255 units (cities or counties) from the 2013 National Central Cancer Registry. Life expectancy data at the unit level were obtained from the National Centers for Disease Control and Prevention. Linear regression analysis was used to analyze the relationship between life expectancy and crude incidence and mortality rates of cancer. In a separate analysis, life expectancy was rated as low (< 76.0 years), middle (76–80 years), or high (> 80 years). Overall, the cancer incidence and mortality rates positively correlated with life expectancy in both sexes (R at 0.37 and 0.50, P < 0.001). The correlation was significant for the following cancers: lung, colorectal, prostate, bladder and pancreas, as well as for lymphoma in men (R 0.36–0.58, P < 0.001), lung, breast, colorectal, thyroid, uterus, and ovary in women (R 0.18–0.51, P < 0.001). We failed to observe an association between upper gastrointestinal cancer and life expectancy. The number of cities/counties with low, middle and high life expectancy levels were 110, 101 and 44, respectively. The highest age-standardized cancer incidence rate was observed in areas with a high life expectancy level (192.83/100,000). The highest age-standardized mortality rate was in areas with the lowest life expectancy (118.44/100,000). Cancers of the stomach, liver and esophagus are major cancer types in areas with low and middle life expectancy. In contrast, areas with high life expectancy had high incidence and mortality rates of colorectal cancer, breast cancer in women and prostate cancer in men. Longer life expectancy is associated with higher overall cancer incidence and mortality in China. The cancer pattern also varies substantially across areas with different life expectancy levels. Life expectancy levels must be considered when developing strategies to prevent and treat cancers.
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DOI：
10.1001/jama.2016.4226
发表时间：
2016-04-26
期刊：
JAMA
影响因子：
--
作者：
Chetty R;Stepner M;Abraham S;Lin S;Scuderi B;Turner N;Bergeron A;Cutler D
通讯作者：
Cutler D
女性乳腺癌发病率和死亡率的全球模式不断变化。
影响因子：
7.4
作者：
Bray, F;McCarron, P;Parkin, DM
通讯作者：
Parkin, DM
影响因子：
7.7
作者：
Hendi, Arun S.
通讯作者：
Hendi, Arun S.
影响因子：
7.8
作者：
Davies, Louise;Welch, H. Gilbert
通讯作者：
Welch, H. Gilbert
2013年中国癌症发病率和死亡率
影响因子：
9.7
作者：
Chen, Wanqing;Zheng, Rongshou;He, Jie
通讯作者：
He, Jie