Human protein reference database--2006 update.

Human protein reference database--2006 update.
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DOI:
10.1093/nar/gkj141
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发表时间:
2006-01-01
影响因子:
14.9
通讯作者:
Pandey A
Pandey A
中科院分区:
生物学2区
文献类型:
--
作者:
Mishra GR;Suresh M;Kumaran K;Kannabiran N;Suresh S;Bala P;Shivakumar K;Anuradha N;Reddy R;Raghavan TM;Menon S;Hanumanthu G;Gupta M;Upendran S;Gupta S;Mahesh M;Jacob B;Mathew P;Chatterjee P;Arun KS;Sharma S;Chandrika KN;Deshpande N;Palvankar K;Raghavnath R;Krishnakanth R;Karathia H;Rekha B;Nayak R;Vishnupriya G;Kumar HG;Nagini M;Kumar GS;Jose R;Deepthi P;Mohan SS;Gandhi TK;Harsha HC;Deshpande KS;Sarker M;Prasad TS;Pandey A

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人类蛋白质参考数据库(HPRD)()是一个全面收集蛋白质特征、翻译后修饰(PTM)和蛋白质-蛋白质相互作用的数据库。自最初的报告以来,该数据库已增加到> 20 000个蛋白质条目,并已成为文献衍生的蛋白质-蛋白质相互作用(> 30 000)和人类蛋白质的PTM(> 8000)的最大数据库。我们还在HPRD中引入了几个新功能,包括:(i)蛋白质异构体,(ii)增强的搜索选项,(iii)连接途径注释和(iv)整合我们开发的新型浏览器GenProt Viewer(),该浏览器允许整合基因组和蛋白质组信息。在生物医学界的持续支持和积极参与下,我们期望HPRD成为人类蛋白质组的独特信息来源,并基于基因组学,转录组学和蛋白质组学数据的整合促进生物医学发现。
Human Protein Reference Database (HPRD) () was developed to serve as a comprehensive collection of protein features, post-translational modifications (PTMs) and protein–protein interactions. Since the original report, this database has increased to >20 000 proteins entries and has become the largest database for literature-derived protein–protein interactions (>30 000) and PTMs (>8000) for human proteins. We have also introduced several new features in HPRD including: (i) protein isoforms, (ii) enhanced search options, (iii) linking of pathway annotations and (iv) integration of a novel browser, GenProt Viewer (), developed by us that allows integration of genomic and proteomic information. With the continued support and active participation by the biomedical community, we expect HPRD to become a unique source of curated information for the human proteome and spur biomedical discoveries based on integration of genomic, transcriptomic and proteomic data.
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发表时间: 2002-01-08
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