Effect of low-intensity pulsed ultrasound stimulation on callus remodelling in a gap-healing model: evaluation by bone morphometry using three-dimensional quantitative micro-CT.
Effect of low-intensity pulsed ultrasound stimulation on callus remodelling in a gap-healing model: evaluation by bone morphometry using three-dimensional quantitative micro-CT.
复制标题
低强度脉冲超声刺激对间隙愈合模型中愈伤组织重塑的影响：使用三维定量显微 CT 进行骨形态测量评估。
DOI：
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复制
发表时间：
2011
影响因子：
--
通讯作者：
Kozo Nakamura
中科院分区：
文献类型：
--
作者：
K. Tobita;I. Ohnishi;T. Matsumoto;S. Ohashi;M. Bessho;M. Kaneko;J. Matsuyama;Kozo Nakamura
We evaluated the effect of low-intensity pulsed ultrasound stimulation (LIPUS) on the remodelling of callus in a rabbit gap-healing model by bone morphometric analyses using three-dimensional quantitative micro-CT. A tibial osteotomy with a 2 mm gap was immobilised by rigid external fixation and LIPUS was applied using active translucent devices. A control group had sham inactive transducers applied. A region of interest of micro-CT was set at the centre of the osteotomy gap with a width of 1 mm. The morphometric parameters used for evaluation were the volume of mineralised callus (BV) and the volumetric bone mineral density of mineralised tissue (mBMD). The whole region of interest was measured and subdivided into three zones as follows: the periosteal callus zone (external), the medullary callus zone (endosteal) and the cortical gap zone (intercortical). The BV and mBMD were measured for each zone. In the endosteal area, there was a significant increase in the density of newly formed callus which was subsequently diminished by bone resorption that overwhelmed bone formation in this area as the intramedullary canal was restored. In the intercortical area, LIPUS was considered to enhance bone formation throughout the period of observation. These findings indicate that LIPUS could shorten the time required for remodelling and enhance the mineralisation of callus.
生长激素未能改变兔子模型骨折愈合的生物力学。
DOI：
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发表时间：
1992
期刊：
The Journal of bone and joint surgery. American volume
影响因子：
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作者：
Carpenter,JE;Hipp,JA;Gerhart,TN;Rudman,CG;Hayes,WC;Trippel,SB
通讯作者：
Trippel,SB
影响因子：
2.3
作者：
Pilla, A A;Mont, M A;Siffert, R S
通讯作者：
Siffert, R S
外部固定器夹具的重复使用会降低夹具的机械性能。
DOI：
10.1111/j.1532-950x.2009.00521.x
发表时间：
2009
期刊：
Veterinary surgery : VS
影响因子：
--
作者：
Gilley,RobertS;Beason,DavidP;Snyder,DavidM;Boston,RaymondC;Radin,Alex;Kapatkin,AmyS;Smith,GailK;Soslowsky,LouisJ
通讯作者：
Soslowsky,LouisJ