Impairment in recognition memory may be associated with near-term risk for suicide attempt in a high-risk sample.
Impairment in recognition memory may be associated with near-term risk for suicide attempt in a high-risk sample.
复制标题
在高风险样本中，识别记忆受损可能与近期自杀企图风险有关。
DOI：
10.1016/j.jad.2024.01.018
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发表时间：
2024
影响因子：
6.6
通讯作者：
Interian,Alejandro
中科院分区：
文献类型：
--
作者：
Myers,CatherineE;DelPozzo,Jill;Perskaudas,Rokas;Dave,ChintanV;Chesin,MeganS;Keilp,JohnG;Kline,Anna;Interian,Alejandro
先前的工作已经涉及到几个神经认知领域，包括记忆，在有自杀企图史的患者中。目前的研究评估是否延迟识别测试可以提高前瞻性预测近期自杀结果的患者样本中的高风险suicide.Methods132退伍军人在高风险自杀完成了基于计算机的识别记忆测试，包括语义相关和无关的话。结果被编码为实际的自杀企图（阿萨），其他自杀相关事件（WASHSE），如流产/中断的企图或准备行为，或两者都没有（NOSE），在90天内testing.ResultsReduced性能是一个显着的预测即将阿萨，但不是WASHSE，控制标准的临床变量，如目前的自杀意念和历史上的自杀企图。然而，与鼻子参照组相比，鼻子参照组在识别熟悉的单词时，语义相关性的预期益处减少了。一个计算模型，漂移扩散模型（DDM），探索潜在的认知过程，揭示了BROSE组的决策效率降低语义相关相比，语义无关的熟悉words.LimitationsThis研究是一个现有的数据集的二次分析，涉及参与者在治疗试验，并需要复制;约10%的样本由于未能掌握练习任务和/或明显的不依从性而被排除在分析之外。并且可以提供一种工具来改进对处于危险中的个体何时可能转变为自杀企图的高风险期的预测。
IntroductionPrior work has implicated several neurocognitive domains, including memory, in patients with a history of prior suicide attempt. The current study evaluated whether a delayed recognition test could enhance prospective prediction of near-term suicide outcomes in a sample of patients at high-risk for suicide.Methods132 Veterans at high-risk for suicide completed a computer-based recognition memory test including semantically-related and -unrelated words. Outcomes were coded as actual suicide attempt (ASA), other suicide-related event (OtherSE) such as aborted/interrupted attempt or preparatory behavior, or neither (noSE), within 90 days after testing.ResultsReduced performance was a significant predictor of upcoming ASA, but not OtherSE, after controlling for standard clinical variables such as current suicidal ideation and history of prior suicide attempt. However, compared to the noSE reference group, the OtherSE group showed a reduction in the expected benefit of semantic relatedness in recognizing familiar words. A computational model, the drift diffusion model (DDM), to explore latent cognitive processes, revealed the OtherSE group had decreased decisional efficiency for semantically-related compared to semantically-unrelated familiar words.LimitationsThis study was a secondary analysis of an existing dataset, involving participants in a treatment trial, and requires replication; ~10 % of the sample was excluded from analysis due to failure to master the practice tasks and/or apparent noncompliance.ConclusionImpairments in recognition memory may be associated with near-term risk for suicide attempt, and may provide a tool to improve prediction of when at-risk individuals may be transitioning into a period of heightened risk for suicide attempt.
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影响因子：
11.3
作者：
Interian, Alejandro;Myers, Catherine E.;Keilp, John G.
通讯作者：
Keilp, John G.
影响因子：
5.7
作者：
Schober P;Vetter TR
通讯作者：
Vetter TR
注意力控制可以通过基于正念的认知疗法来预防自杀。
影响因子：
4.1
作者：
Megan S. Chesin;J. Keilp;A. Kline;Barbara Stanley;C. Myers;Miriam Latorre;Lauren M St Hill;Rachael B. Miller;Arlene R. King;Dianna R. Boschulte;Kailyn M. Rodriguez;Michael Callahan;Megan Sedita;A. Interian
通讯作者：
A. Interian
影响因子：
3.1
作者：
Goddard, L;Dritschel, B;Burton, A
通讯作者：
Burton, A
影响因子：
14.5
作者：
Savage, CR;Deckersbach, T;Rauch, SL
通讯作者：
Rauch, SL