Implications of adopting the WHO 2006 Child Growth Standard in the UK: two prospective cohort studies.
Implications of adopting the WHO 2006 Child Growth Standard in the UK: two prospective cohort studies.
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DOI：
10.1136/adc.2007.126854
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发表时间：
2008-07
影响因子：
5.2
通讯作者：
Ong KK
中科院分区：
文献类型：
--
作者：
Wright C;Lakshman R;Emmett P;Ong KK
世卫组织2006年儿童生长标准是基于国际最佳营养母乳喂养婴儿从出生到5岁的数据。评估其使用对英国儿童体重和生长监测的潜在影响。两个基于人群的英国出生队列的足月成员：雅芳父母和儿童纵向研究（ALSPAC）的焦点儿童子队列（n = 1335）和盖茨黑德千禧婴儿研究（GMS; n = 923）。 从出生到5岁的生长数据被转换为相对于WHO 2006标准的z分数。与WHO标准相比，两个英国队列的出生体重更高（平均z评分：GMS，0.17; ALSPAC，0.34），ALSPAC的出生身长更高。出生后，所有年龄段的长度都显示出良好的拟合。到2-4个月时，两个队列的体重与WHO中位数相似（4个月时的平均WHO体重z评分：GMS，0.01; ALSPAC，-0.07），但此后英国队列更重（12个月时的平均WHO体重z评分：GMS，0.57; ALSPAC，0.65）。在12个月大时，根据WHO标准，被归类为体重不足（体重<第2百分位数）的风险显著低于英国1990年生长参考（RR = 0.15，95% CI = 0.07至0.32），在4-5岁时被归类为肥胖（体重指数>第98百分位数）的风险略有增加（RR = 1.35，95% CI = 1.02至1.78）。 采用世卫组织2006年生长图表将为英国婴儿4个月以上的体重增加设定一个明显较低的标准，并可支持避免未来儿童肥胖的努力。然而，世界卫生组织的标准并不能代表英国出生时的体型。
The WHO 2006 Child Growth Standard is based on data from international optimally nourished breastfed infants from birth to age 5 years. To assess the potential effect of its use on weight and growth monitoring of UK children. Full-term members of two population-based UK birth cohorts: the Children in Focus sub-cohort of the Avon Longitudinal Study of Parents and Children (ALSPAC) (n = 1335) and the Gateshead Millennium Baby Study (GMS; n = 923). Growth data from birth to 5 years were converted into z-scores relative to the WHO 2006 standard. Compared with the WHO standard, both UK cohorts had higher birth weights (mean z-scores: GMS, 0.17; ALSPAC, 0.34) and ALSPAC had higher birth lengths. After birth, length showed a good fit at all ages. By 2–4 months, both cohorts were similar in weight to the WHO median (mean WHO weight z-score at 4 months: GMS, 0.01; ALSPAC, −0.07), but thereafter the UK cohorts were heavier (mean WHO weight z-score at 12 months: GMS, 0.57; ALSPAC, 0.65). At age 12 months, the risk of being classified as underweight (weight <2nd centile) was considerably lower according to the WHO standard than by the UK 1990 Growth Reference (RR = 0.15, 95% CI = 0.07 to 0.32), and the risk of being classified as obese at 4–5 years (body mass index >98th centile) was slightly increased (RR = 1.35, 95% CI = 1.02 to 1.78). Adoption of the WHO 2006 Growth Charts would set a markedly lower standard of weight gain beyond the age of 4 months for UK infants and could support efforts to avoid future childhood obesity. However, the WHO standard is not representative of size at birth in the UK.
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影响因子：
3.8
作者：
Garza, Cutberto;de Onis, Mercedes;Martines, Jose
通讯作者：
Martines, Jose
影响因子：
--
作者：
Reilly, JJ;Dorosty, AR;Emmett, PM
通讯作者：
Emmett, PM
影响因子：
5.2
作者：
Spencer, N. J.
通讯作者：
Spencer, N. J.
DOI：
10.1136/adc.2003.026906
发表时间：
2004-05-01
影响因子：
4.4
作者：
Wright, CM;Parkinson, KN
通讯作者：
Parkinson, KN
影响因子：
3.8
作者：
de Onis, Mercedes;Onyango, Adelheid;Heinig, M. Jane
通讯作者：
Heinig, M. Jane