How complex are the editosomes in plant organelles?
How complex are the editosomes in plant organelles?
复制标题
植物细胞器中的编辑体有多复杂？
DOI：
10.1093/mp/sst170
复制
发表时间：
2014
期刊：
影响因子：
27.5
通讯作者：
Takenaka
中科院分区：
文献类型：
--
作者：
Takenaka
在大多数陆地植物的叶绿体和线粒体中，RNA编辑修饰特定的核苷酸。通过其序列背景来识别任一细胞器的复杂RNA分子群体中的单个核苷酸。生物化学反应实际上是显花植物中的C-to-U脱氨基反应，此外，蕨类植物和金鱼藻中也发生U-to-C氨基化反应。RNA序列鉴定步骤由特异性RNA结合蛋白PPR蛋白完成，但催化编辑反应的酶仍然未知。然而，最近已经鉴定出另外的蛋白质，其是细胞器RNA编辑所需的或至少影响细胞器RNA编辑。几种蛋白质的复杂组装似乎在叶绿体和线粒体中建立起功能性编辑体。
In chloroplasts and mitochondria of most land plants, RNA editing modifies specific nucleotides. The individual nucleotides are identified in the complex RNA molecule population of either organelle by their sequence context. The biochemical reaction is in effect a C-to-U deamination in flowering plants, in addition a U-to-C amination reaction occurs in ferns and hornworts.The RNA sequence identification step is performed by specific RNA binding proteins, the PPR proteins, but the enzymes catalyzing the editing reactions are still unknown. However, additional proteins have recently been identified which are required for or at least influence organellar RNA editing. A complex assembly of several proteins appears to build up the functional editosomes in chloroplasts and in mitochondria.
改进了五肽重复 RNA 编辑因子的计算靶位点预测。
影响因子：
3.7
作者：
Takenaka M;Zehrmann A;Brennicke A;Graichen K
通讯作者：
Graichen K
DOI：
10.1073/pnas.1202452109
发表时间：
2012-03-27
影响因子：
11.1
作者：
Takenaka, Mizuki;Zehrmann, Anja;Brennicke, Axel
通讯作者：
Brennicke, Axel
影响因子：
4.8
作者：
Hayes, Michael L.;Giang, Karolyn;Mulligan, R. Michael
通讯作者：
Mulligan, R. Michael