Activated porcine alveolar macrophages: are biological response modifiers the answer?
Activated porcine alveolar macrophages: are biological response modifiers the answer?
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DOI：
10.1016/0165-2427(89)90166-9
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发表时间：
1989-08
影响因子：
1.8
通讯作者：
Blecha F
中科院分区：
文献类型：
--
作者：
Chapes SK;Chitko CG;Thaler RC;Nelssen JL;Anderson GA;Blecha F
We report that 75% of conventionally housed 3- to 4-week-old swine already have detectable activated alveolar macrophages as measured by cytotoxicity of tumor cells. These macrophages can not be further activated by the biological response modifier N-acetylmuramyl-L-alanyl-D-isoglutamine-2H2O (MDP). These macrophages lose cytotoxic activity when cultured for 24 h and this loss of activity can not be reversed by MDP. We suggest that MDP biological response modifier therapy of swine alveolar macrophages may not be a useful technique in preventing respiratory disease in swine.
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影响因子：
56.9
作者：
EDWARDS, CK;GHIASUDDIN, SM;KELLEY, KW
通讯作者：
KELLEY, KW
DOI：
10.1016/0147-9571(86)90007-x
发表时间：
1986-01-01
影响因子：
2
作者：
CHARLEY, B
通讯作者：
CHARLEY, B
影响因子：
1.8
作者：
CHARLEY, B;PETIT, E;LECLERC, C
通讯作者：
LECLERC, C
影响因子：
3.8
作者：
LAUDE, H;CHARLEY, B;GELFI, J
通讯作者：
GELFI, J
影响因子：
56.9
作者：
KOFF, WC;SHOWALTER, SD;FIDLER, IJ
通讯作者：
FIDLER, IJ