Cold stress related alteration of RNA biosynthesis in brain cortex of mother-deprived newborn rats.
Cold stress related alteration of RNA biosynthesis in brain cortex of mother-deprived newborn rats.
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寒冷应激相关的剥夺母亲的新生大鼠大脑皮层 RNA 生物合成的改变。
DOI：
10.1016/s0024-3205(97)00231-2
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发表时间：
1997
期刊：
影响因子：
6.1
通讯作者：
J. Azcurra
中科院分区：
文献类型：
--
作者：
G. R. Ibarra;G. Paratcha;J. Rodriquez;M. Napp;J. Azcurra
We studied the influence of maternal deprivation on the RNA biosynthesis in the brain cortex of 10 day-old rats. Mother-deprived pups, placed at 25 °C showed a reduction in body temperature of 6 +/− 1 °C. After mother retrieval, RNA biosynthesis decreased 27% and 34% in total brain cortex and in isolated neurons, respectively. This fall is proportional to the body temperature reduction and can be avoided placing the pups at 37 °C immediately after the separation. Rethermostatization of offsprings, after one hour at 25 °C, showed an overshoot of RNA biosynthesis (145%) with further stabilization of synthesis rates to normal levels after 100 min. This classical physiological mechanism was further studied in vitro. Comparing in vivo and in vitro experiments, it is concluded that overshooting can not be observed in vitro if temperature reduction was not previously performed in vivo. Thus, this phenomenon seems to respond to humoral factors in order to be triggered. Afterwards, in vitro overshooting following cold stress in vivo, demonstrates that the depressed tissue by itself has the capability to turn back to normal RNA levels in the same way as observed in vivo.
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母体分离对大鼠生长、活动和安非他明敏感性的温度依赖性影响。
影响因子：
2.2
作者：
Zimmerberg,B;Shartrand,AM
通讯作者：
Shartrand,AM
影响因子：
4.1
作者：
Deborah Suchecki;D. Mozaffarian;Graziella Gross;P. Rosenfeld;Seymour Levine
通讯作者：
Deborah Suchecki;D. Mozaffarian;Graziella Gross;P. Rosenfeld;Seymour Levine
依恋、失落和抑郁。
DOI：
10.1111/j.1469-7610.1981.tb00539.x
发表时间：
1981
期刊：
Journal of child psychology and psychiatry, and allied disciplines
影响因子：
--
作者：
Reite,M;Short,R;Seiler,C;Pauley,JD
通讯作者：
Pauley,JD
影响因子：
2.2
作者：
KUHN, CM;PAUK, J;SCHANBERG, SM
通讯作者：
SCHANBERG, SM