Fabrication of Parylene-Coated Microneedle Array Electrode for Wearable ECG Device.
Fabrication of Parylene-Coated Microneedle Array Electrode for Wearable ECG Device.
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DOI：
10.3390/s20185183
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发表时间：
2020-09-11
期刊：
影响因子：
--
通讯作者：
Cho S
中科院分区：
文献类型：
--
作者：
Satti AT;Park J;Park J;Kim H;Cho S
微针阵列电极（MNE）通过穿透具有高电阻抗的角质层而显示出巨大的潜力，用于灵敏地监测生物电信号。本文介绍了一种刚性聚对二甲苯涂层微针电极阵列和便携式心电图（ECG）电路，用于心电监测，减少运动伪影。与典型的银-氯化银（Ag/AgCl）湿电极相比，开发的MNE显示出动态和长期ECG监测的稳定性和耐用性。微针在高达16 N的压缩力下未显示出机械失效，但在5 N的低插入力下成功穿透皮肤组织。利用阻抗谱和等效电路模型对所制备的MNE的电学特性进行了表征。所设计的可穿戴式无线心电监护设备与MNE证明了心电记录的可行性，减少了运动伪影的噪声在动态行为。
Microneedle array electrodes (MNE) showed immense potential for the sensitive monitoring of the bioelectric signals by penetrating the stratum corneum with high electrical impedance. In this paper, we introduce a rigid parylene coated microneedle electrode array and portable electrocardiography (ECG) circuit for monitoring of ECG reducing the motion artifacts. The developed MNE showed stability and durability for dynamic and long-term ECG monitoring in comparison to the typical silver-silver chloride (Ag/AgCl) wet electrodes. The microneedles showed no mechanical failure under the compression force up-to 16 N, but successful penetration of skin tissue with a low insertion force of 5 N. The electrical characteristics of the fabricated MNE were characterized by impedance spectroscopy with equivalent circuit model. The designed wearable wireless ECG monitoring device with MNE proved feasibility of the ECG recording which reduces the noise of movement artifacts during dynamic behaviors.
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DOI：
10.1016/j.jconrel.2019.11.023
发表时间：
2020-01-10
期刊：
Journal of controlled release : official journal of the Controlled Release Society
影响因子：
--
作者：
Balmert SC;Carey CD;Falo GD;Sethi SK;Erdos G;Korkmaz E;Falo LD Jr
通讯作者：
Falo LD Jr
影响因子：
4.6
作者：
Dias, N. S.;Carmo, J. P.;Correia, J. H.
通讯作者：
Correia, J. H.
DOI：
10.3390/s150716265
发表时间：
2015-07-06
期刊：
Sensors (Basel, Switzerland)
影响因子：
--
作者：
Kim M;Kim T;Kim DS;Chung WK
通讯作者：
Chung WK
影响因子：
4.6
作者：
Baek, Ju-Yeoul;An, Jin-Hee;Lee, Sang-Hoon
通讯作者：
Lee, Sang-Hoon
影响因子：
17.6
作者：
Chi, Yu Mike;Jung, Tzyy-Ping;Cauwenberghs, Gert
通讯作者：
Cauwenberghs, Gert