The Mouse Genome Database: integration of and access to knowledge about the laboratory mouse.
The Mouse Genome Database: integration of and access to knowledge about the laboratory mouse.
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DOI：
10.1093/nar/gkt1225
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发表时间：
2014-01
影响因子：
14.9
通讯作者：
Mouse Genome Database Group
中科院分区：
文献类型：
--
作者：
Blake JA;Bult CJ;Eppig JT;Kadin JA;Richardson JE;Mouse Genome Database Group
小鼠基因组数据库 (MGD) (http://www.informatics.jax.org) 是实验室小鼠的群落模型生物数据库资源，是研究与人类生物学和疾病相关的遗传和基因组系统的首要动物模型。 MGD 维护着基因、功能性 RNA 和其他基因组特征以及可遗传表型和数量性状基因座的综合目录。基因组特征目录是通过整合 NCBI、Ensembl 和 Vega/HAVANA 生成的计算和手动基因组注释而生成的。 MGD 使用基因本体管理和维护小鼠基因功能注释的全面列表，MGD 管理和整合全面的表型注释，包括小鼠模型与人类疾病的关联。最近的改进包括集成最新的小鼠基因组构建 (GRCm38)、通过扩展比较脊椎动物基因组的代表性以及来自高通量表型项目的新表型数据负载，改进了对小鼠基因的比较和功能注释的访问。所有 MGD 资源均可免费提供给研究界。
The Mouse Genome Database (MGD) (http://www.informatics.jax.org) is the community model organism database resource for the laboratory mouse, a premier animal model for the study of genetic and genomic systems relevant to human biology and disease. MGD maintains a comprehensive catalog of genes, functional RNAs and other genome features as well as heritable phenotypes and quantitative trait loci. The genome feature catalog is generated by the integration of computational and manual genome annotations generated by NCBI, Ensembl and Vega/HAVANA. MGD curates and maintains the comprehensive listing of functional annotations for mouse genes using the Gene Ontology, and MGD curates and integrates comprehensive phenotype annotations including associations of mouse models with human diseases. Recent improvements include integration of the latest mouse genome build (GRCm38), improved access to comparative and functional annotations for mouse genes with expanded representation of comparative vertebrate genomes and new loads of phenotype data from high-throughput phenotyping projects. All MGD resources are freely available to the research community.
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影响因子：
14.9
作者：
NCBI Resource Coordinators
通讯作者：
NCBI Resource Coordinators
影响因子：
14.9
作者：
Blake JA;Bult CJ;Eppig JT;Kadin JA;Richardson JE;Mouse Genome Database Group
通讯作者：
Mouse Genome Database Group
影响因子：
12.3
作者：
Yalcin B;Wong K;Bhomra A;Goodson M;Keane TM;Adams DJ;Flint J
通讯作者：
Flint J
影响因子：
2.4
作者：
Begley, D. A.;Krupke, D. M.;Sundberg, J. P.
通讯作者：
Sundberg, J. P.
影响因子：
14.9
作者：
Gene Ontology Consortium;Blake JA;Dolan M;Drabkin H;Hill DP;Li N;Sitnikov D;Bridges S;Burgess S;Buza T;McCarthy F;Peddinti D;Pillai L;Carbon S;Dietze H;Ireland A;Lewis SE;Mungall CJ;Gaudet P;Chrisholm RL;Fey P;Kibbe WA;Basu S;Siegele DA;McIntosh BK;Renfro DP;Zweifel AE;Hu JC;Brown NH;Tweedie S;Alam-Faruque Y;Apweiler R;Auchinchloss A;Axelsen K;Bely B;Blatter M-;Bonilla C;Bouguerleret L;Boutet E;Breuza L;Bridge A;Chan WM;Chavali G;Coudert E;Dimmer E;Estreicher A;Famiglietti L;Feuermann M;Gos A;Gruaz-Gumowski N;Hieta R;Hinz C;Hulo C;Huntley R;James J;Jungo F;Keller G;Laiho K;Legge D;Lemercier P;Lieberherr D;Magrane M;Martin MJ;Masson P;Mutowo-Muellenet P;O'Donovan C;Pedruzzi I;Pichler K;Poggioli D;Porras Millán P;Poux S;Rivoire C;Roechert B;Sawford T;Schneider M;Stutz A;Sundaram S;Tognolli M;Xenarios I;Foulgar R;Lomax J;Roncaglia P;Khodiyar VK;Lovering RC;Talmud PJ;Chibucos M;Giglio MG;Chang H-;Hunter S;McAnulla C;Mitchell A;Sangrador A;Stephan R;Harris MA;Oliver SG;Rutherford K;Wood V;Bahler J;Lock A;Kersey PJ;McDowall DM;Staines DM;Dwinell M;Shimoyama M;Laulederkind S;Hayman T;Wang S-;Petri V;Lowry T;D'Eustachio P;Matthews L;Balakrishnan R;Binkley G;Cherry JM;Costanzo MC;Dwight SS;Engel SR;Fisk DG;Hitz BC;Hong EL;Karra K;Miyasato SR;Nash RS;Park J;Skrzypek MS;Weng S;Wong ED;Berardini TZ;Huala E;Mi H;Thomas PD;Chan J;Kishore R;Sternberg P;Van Auken K;Howe D;Westerfield M
通讯作者：
Westerfield M