Advanced Endoscopic Imaging and Interventions in GERD: An Update and Future Directions.
Advanced Endoscopic Imaging and Interventions in GERD: An Update and Future Directions.
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DOI：
10.3389/fmed.2021.728696
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发表时间：
2021
影响因子：
3.9
通讯作者：
Umapathy C
中科院分区：
文献类型：
--
作者：
Mann R;Gajendran M;Perisetti A;Goyal H;Saligram S;Umapathy C
胃食管反流病（GERD）是一种最常见的胃肠道疾病，在初级保健和胃肠病诊所。大多数GERD病例可以根据临床表现和风险因素进行诊断;然而，一些患者存在非典型症状，这可能使诊断困难。食管胃管镜检查可用于辅助诊断GERD，尽管这些患者中只有一半在标准白色光内镜下有可见的内镜检查结果。这导致了新的先进内镜技术的发展，增强了GERD和相关并发症（如鳞状细胞发育不良、Barrett食管和早期食管腺癌）的诊断。这是通过实时光学活检对粘膜和血管结构中细微不规则性的改进检测来进行的。GERD的管理包括生活方式的改变，药物治疗，内镜和手术干预。微创内窥镜介入治疗可以作为小食管裂孔疝且无GERD并发症患者的一种选择。这些内窥镜介入包括内窥镜胃底折叠术、内窥镜粘膜切除技术、消融技术、创建机械屏障以及吻合器和吻合器械。随着这些新的先进内窥镜技术的出现，需要彻底了解这些技术的适应症、优点和缺点。
Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal diseases encountered in primary care and gastroenterology clinics. Most cases of GERD can be diagnosed based on clinical presentation and risk factors; however, some patients present with atypical symptoms, which can make diagnosis difficult. An esophagogastroduodenoscopy can be used to assist in diagnosis of GERD, though only half of these patients have visible endoscopic findings on standard white light endoscopy. This led to the development of new advanced endoscopic techniques that enhanced the diagnosis of GERD and related complications like squamous cell dysplasia, Barrett's esophagus, and early esophageal adenocarcinoma. This is conducted by improved detection of subtle irregularities in the mucosa and vascular structures through optical biopsies in real-time. Management of GERD includes lifestyle modifications, pharmacological therapy, endoscopic and surgical intervention. Minimally invasive endoscopic intervention can be an option in selected patients with small hiatal hernia and without complications of GERD. These endoscopic interventions include endoscopic fundoplication, endoscopic mucosal resection techniques, ablative techniques, creating mechanical barriers, and suturing and stapling devices. As these new advanced endoscopic techniques are emerging, data surrounding the indications, advantages and disadvantages of these techniques need a thorough understanding.
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发表时间：
2021-11
期刊：
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影响因子：
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发表时间：
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影响因子：
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