Recognition of specific targets by cultured dorsal root ganglion neurons
Recognition of specific targets by cultured dorsal root ganglion neurons
复制标题
培养的背根神经节神经元对特定目标的识别
DOI:
10.1523/jneurosci.07-08-02305.1987
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发表时间:
1987
影响因子:
--
通讯作者:
M. Fishman
中科院分区:
文献类型:
--
作者:
L. Baizer;M. Fishman
We have assessed the effects of different target cell populations on axonally transported proteins by the use of compartmental cell culture systems that separate the soma from the growing axons of rat sensory neurons. The labeling of 3 rapidly transported proteins diminishes when the growing axon contacts spinal cord cells (which are normal in vivo targets), and remains unaffected by contact with fibroblasts or heart cells. Medium conditioned by spinal cord cells does not exert this effect. Thus, specific classes of cells may be distinguished as target tissue by sensory neurons in vitro. Such recognition is accompanied by specific molecular changes in axonally transported proteins.
影响因子:
13.9
作者:
Berg,DK
通讯作者:
Berg,DK
DOI:
10.1073/pnas.83.10.3537
发表时间:
1986-05-01
影响因子:
11.1
作者:
MEIRI, KF;PFENNINGER, KH;WILLARD, MB
通讯作者:
WILLARD, MB
影响因子:
56.9
作者:
COWAN, WM;FAWCETT, JW;STANFIELD, BB
通讯作者:
STANFIELD, BB