Effects of work and life stress on semen quality.

Effects of work and life stress on semen quality.
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DOI:
10.1016/j.fertnstert.2014.04.021
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发表时间:
2014-08
影响因子:
6.7
通讯作者:
Factor-Litvak, Pam
Factor-Litvak, Pam
中科院分区:
医学2区
文献类型:
--
作者:
Janevic, Teresa;Kahn, Linda G.;Landsbergis, Paul;Cirillo, Piera M.;Cohn, Barbara A.;Liu, Xinhua;Factor-Litvak, Pam

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评估与工作有关的压力,压力性生活事件,感知压力和精液质量之间的关联。横截面分析。北方加州。2005-2008年期间,对儿童健康和发展研究中的193名男子进行了评价。没有。测量压力,包括工作压力,感知压力和压力性生活事件;测量精子浓度,活动精子百分比和形态正常精子百分比的结果。我们发现压力感知得分和精子浓度之间呈负相关(估计系数B = -0.09 × 103/mL; 95%置信区间[CI] =-0.18,-0.01),运动性在协变量调整的线性回归分析中,(B = -0.39,95% CI =-0.79,0.01)和形态学(B = -0.14,95% CI,-0.25,-0.04)。在过去的一年中经历过两次或两次以上压力性生活事件的男性与没有经历过压力性生活事件的男性相比,活动精子的百分比较低(B= -8.22; 95% CI,-14.31,-2.13),形态正常的精子百分比较低(B = -1.66; 95% CI,-3.35,0.03),但精子浓度相似。工作紧张与精液参数无关。在这第一项研究中,研究了压力的所有三个领域,感知压力和压力性生活事件,但与工作有关的压力与精液质量有关。
To evaluate associations between work-related stress, stressful life events, and perceived stress and semen quality. Cross-sectional analysis. Northern California. 193 men from the Child Health and Development Studies evaluated between 2005–2008. None. Measures of stress including job strain, perceived stress, and stressful life events; outcome measures of sperm concentration, percentage of motile sperm, and percentage of morphologically normal sperm. We found an inverse association between perceived stress score and sperm concentration (estimated coefficient b = –0.09 × 103/mL; 95% confidence interval [CI] = –0.18, –0.01), motility (b = –0.39; 95% CI = –0.79, 0.01), and morphology (b = –0.14; 95% CI, –0.25, –0.04) in covariate-adjusted linear regression analyses. Men who experienced two or more stressful life events in the past year compared with no stressful events had a lower percentage of motile sperm (b= –8.22; 95% CI, –14.31, –2.13) and a lower percentage of morphologically normal sperm (b = –1.66; 95% CI, –3.35, 0.03) but a similar sperm concentration. Job strain was not associated with semen parameters. In this first study to examine all three domains of stress, perceived stress and stressful life events but not work-related stress were associated with semen quality.
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