Analysis of Clinical Manifestations and Imaging of COVID-19 Patients in Intensive Care.
Analysis of Clinical Manifestations and Imaging of COVID-19 Patients in Intensive Care.
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分析重症监护术中199名患者的临床表现和成像。
DOI：
10.1155/2022/9697285
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发表时间：
2022
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本研究旨在总结和分析重症COVID-19患者的临床和CT表现。 回顾性分析了2020年2月11日至3月31日同济医院E1-3病房重症监护的61名COVID-19患者。 主要临床表现为咳嗽、咳痰56例（91.8%），气促、胸闷48例（78.7%），发热61例（100%），肌肉酸痛无力40例（65.6%），腹泻或呕吐8例（13.1%），头痛4例（6.6%）。入院后白细胞计数正常40例（57.7%），升高9例（15.4%），降低12例（26.9%）。淋巴细胞计数下降53例（86.9%）。CRP升高29例PCT升高者15例（47.5%）ESR增高38例（24.6%）D-二聚体升高39例ALT/AST升高40例CK/CK-MB升高8例（13.1%）;肌钙蛋白I升高6例NT-proBNP升高35例IL-1升高5例IL-2受体升高28例IL-6升高23例（37.7%），IL-8升高15例（24.6%），IL-10升高12例（19.7%），NTF升高22例（36.1%）。胸部CT显示38例右肺病变较左肺广泛者占65.5%，左肺病变较右肺病变广泛者占34.5%，下叶病变较上叶广泛者占72.5%，上叶病变较下叶广泛者占10.3%，上下叶大致相同者10例占17.2%。磨玻璃影12例（20.7%），磨玻璃影伴局灶性实变38例（65.5%），小片状边缘模糊密度增高24例（41.4%），大片实变20例（34.5%），网状或纤维索影54例（93.1%），支气管充气征8例（13.8%）。 重症监护的COVID-19患者无特异性临床表现和CT表现。但对相关数据的分析和总结可以帮助我们评估疾病的严重程度，决定治疗时机，预测预后。
The study aims to summarize and analyze the clinical and CT findings of severe COVID-19 patients. From February 11 to March 31, 2020, 61 COVID-19 patients in intensive care in the E1-3 ward of Tongji Hospital were analyzed retrospectively. The main clinical manifestations were cough, expectoration in 56 cases (91.8%), shortness of breath, chest tightness in 48 cases (78.7%), fever in 61 cases (100%), muscle ache and weakness in 40 cases (65.6%), diarrhea or vomiting in 8 cases (13.1%), and headache in 4 cases (6.6%). After admission, the leukocyte count was normal in 40 cases (57.7%), higher in 9 cases (15.4%), and lower in 12 cases (26.9%). The lymphocyte count decreased in 53 cases (86.9%). CRP was increased in 29 cases (47.5%); PCT was increased in 15 cases (24.6%); ESR was increased in 38 cases (62.3%); D-dimer increased in 39 cases (63.9%); ALT/AST increased in 40 cases (65.6%); CK/CK-MB increased in 8 cases (13.1%); troponin I increased in 6 cases (9.8%); NT-proBNP increased in 35 cases (57.4%); IL-1 increased in 5 cases (8.2%); IL-2 receptor increased in 28 cases (45.9%); IL-6 increased in 23 cases (37.7%); IL-8 increased in 15 cases (24.6%); IL-10 increased in 12 cases (19.7%); and NTF increased in 22 cases (36.1%). The chest CT images showed that 38 cases (65.5%) of right lung lesions were more extensive than those of left lung lesions, 20 cases (34.5%) of left lung lesions were more extensive than those of right lung lesions, 42 cases (72.5%) of lower lobe lesions were more extensive than those of upper lobe lesions, 6 cases (10.3%) of upper lobe lesions were more extensive than those of lower lobe lesions, and 10 cases (17.2%) of upper and lower part lesions were roughly the same. Ground-glass opacity (GGO) was found in 12 cases (20.7%); GGO with focal consolidation in 38 cases (65.5%); small patchy edge fuzzy density increased in 24 cases (41.4%); large consolidation in 20 cases (34.5%); reticular or fibrous cord in 54 cases (93.1%); and air bronchogram in 8 cases (13.8%). COVID-19 patients in intensive care have no specific clinical manifestation and CT findings. However, analysis and summary of relevant data can help us assess the severity of the disease, decide the timing of treatment, and predict prognosis.
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发表时间：
2022-12
期刊：
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影响因子：
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