Vascular Geometry Associated with Anterior Communicating Artery Aneurysm Formation.
Vascular Geometry Associated with Anterior Communicating Artery Aneurysm Formation.
复制标题
DOI：
10.1016/j.wneu.2020.11.160
复制
发表时间：
2021-03
影响因子：
2
通讯作者：
Du R
中科院分区：
文献类型：
--
作者：
Zhang J;Can A;Lai PMR;Mukundan S Jr;Castro VM;Dligach D;Finan S;Gainer VS;Shadick NA;Savova G;Murphy SN;Cai T;Weiss ST;Du R
We aimed to identify clinical and morphological risk factors that are correlated with anterior communicating artery (ACoA) aneurysm formation. Three-dimensional morphological parameters obtained from CT-angiography (CTA) or digital subtraction angiography (DSA) from 504 patients with ACoA aneurysms and 201 patients with aneurysms elsewhere, diagnosed at the Brigham and Women’s Hospital and Massachusetts General Hospital between 1990 and 2016 were evaluated. We examined the presence of hypoplastic and aplastic A1 segments, and diameters and angles of surrounding parent and daughter vessels. Univariable and multivariable statistical analyses were performed to determine statistical significance. Sensitivity analyses with small (≤ 3mm) aneurysms only was also performed. Aplastic and hypoplastic A1s were more common in the ACoA group (38.9% vs 6.5% hypoplastic, and 22.2% vs 0.5% aplastic). In multivariable analysis, the presence of an hypoplastic A1 segment was associated with ACoA aneurysms. A2-ACoA (daughter-daughter) angle was also significantly associated with ACoA aneurysms in multivariable analysis, however, since Pearson’s correlation test between aneurysm width and daughter-daughter angle was significant, daughter-daughter angle was most likely not independently associated with aneurysm presence, but may be a result of the presence of an aneurysm. Subgroup analyses of small aneurysms (≤3mm) and of unruptured aneurysms only showed similar results. Our results demonstrate that of all the morphological parameters, the presence of a hypoplastic A1 segment was the only parameter independently associated with the presence of ACoA aneurysms that was uncorrelated with aneurysm size, and could aid as a simple screening parameter.
登录
查看更多内容
分析形态学参数以区分前交通动脉瘤中的破裂状态。
影响因子：
3.7
作者：
Lin N;Ho A;Charoenvimolphan N;Frerichs KU;Day AL;Du R
通讯作者：
Du R
前交通动脉瘤血流模式对脑动脉网络解剖变化的敏感性
影响因子：
2.4
作者：
Liang, Fuyou;Liu, Xiaosheng;Liu, Hao
通讯作者：
Liu, Hao
影响因子：
1.4
作者：
Zurada, Anna;Gielecki, Jerzy;Michalak, Maciej
通讯作者：
Michalak, Maciej
影响因子：
4.1
作者：
Rinaldo, Lorenzo;McCutcheon, Brandon A.;Lanzino, Giuseppe
通讯作者：
Lanzino, Giuseppe
影响因子：
8.3
作者：
KAYEMBE, KNT;SASAHARA, M;HAZAMA, F
通讯作者：
HAZAMA, F