A rat genetic linkage map and comparative maps for mouse or human homologous rat genes

A rat genetic linkage map and comparative maps for mouse or human homologous rat genes
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大鼠遗传连锁图谱以及小鼠或人类同源大鼠基因的比较图谱

DOI:
10.1007/bf00292332
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发表时间:
1994
期刊:
影响因子:
2.5
通讯作者:
Tadao Serikawa
Tadao Serikawa
中科院分区:
生物学4区
文献类型:
--
作者:
Junzo Yamada;T. Kuramoto;Tadao Serikawa

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大鼠(Rattus norvegicus)被广泛用于生物医学研究领域,并已开发出许多人类疾病的动物模型。然而,老鼠的遗传图谱仍然缺乏文献记载。Hedrich(1990)描述了一张由13个组组成的大鼠连锁图谱,其中只有6个组被分配给染色体。莱万及其同事(1991,1992)从文献中收集了映射信息,包括他们自己的作品。他们的表格和图表包含基因染色体分配、细胞遗传学定位以及大鼠G带模式与小鼠和人类的G带模式的比较,但不包括任何关于基因顺序或距离的信息。最近,Serikawa等报道了一个信息丰富的大鼠遗传连锁图(1992 b)。它是基于125个多态性标记在7个大鼠回交和2个F2杂交中的分离,所有的连锁群被分配到特定的染色体。该连锁图和微卫星标记的信息为利用大鼠模型进行人类疾病的遗传研究提供了很大的帮助。从那时起,相当数量的新数据的大鼠连锁图谱出现在几个出版物。因此,我们收集了截至1993年中期发表的映射数据,包括我们最近的报告,并在映射位点列表中对其进行了总结。这个遗传图谱,结合几个连锁数据构建的,和两个比较地图的小鼠或人类同源大鼠基因应该是非常翔实的许多研究人员在大鼠,小鼠或人类的遗传研究。
The rat (Rattus norvegicus) is used in a broad field of biomedical research, and numerous animal models for human diseases have been developed. The rat genetic map, however, remains poorly documented. Hedrich (1990) described a rat linkage map consisting of 13 groups, of which only 6 were assigned to chromosomes. Levan and coworkers (1991, 1992) collected mapping information from the literature, including their own works. Their tables and figures contain gene chromosomal assignments, cytogenetical localizations, and comparisons of the rat G-banding pattern with those of mice and humans, but do not include any information about gene orders or distances. Recently, an informative rat genetic linkage map has been reported by Serikawa and colleagues (1992b). It is based on the segregation of 125 polymorphic markers in seven rat backcrosses and two F 2 crosses, and all of the linkage groups are assigned to particular chromosomes. The linkage map and the information on microsatellite markers became a great help for genetic studies with rat models for human diseases. Since then, a considerable amount of new data for the rat linkage map has appeared in several publications. We, therefore, have collected mapping data published up to the middle of 1993, including our recent reports, and have summarized it here in a list of mapped loci. This genetic map, constructed by combining several linkage data, and two comparative maps for mouse or human homologous rat genes should be very informative to many researchers working on genetic studies in rats, mice, or humans.
新标记 D16FC1 和 Tp12 可区分大鼠 16 号和 17 号染色体。
DOI: 10.1159/000133459
发表时间: 1993
期刊: Cytogenetics and cell genetics
影响因子: --
作者:
Yeung,RS;Taguchi,T;Patriotis,C;Makris,A;Tsichlis,PN;Levan,KK;Levan,G;Tartof,K;Hino,O;Knudson,AG;Testa,JR
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大鼠补体第六成分(C6)的遗传多态性。
DOI: --
发表时间: 1984
期刊: Journal of immunology (Baltimore, Md. : 1950)
影响因子: --
作者:
Granados,J;Cramer,DV;Caputo,JB;Marcus,D;Alper,CA
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DOI: 10.1016/0888-7543(91)90412-8
发表时间: 1991
期刊: Genomics
影响因子: 4.4
作者:
Pravenec,M;Simonet,L;Kren,V;Kunes,J;Levan,G;Szpirer,J;Szpirer,C;Kurtz,T
通讯作者: Kurtz,T
一种独特的胎盘抗原,由 MHC 相关基因座 RT11 控制。
DOI: --
发表时间: 1989
影响因子: 0.9
作者:
Kunz,HW;Ho,HN;Misra,DN;Gill3rd,TJ
通讯作者: Gill3rd,TJ
甲状旁腺激素样肽的基因位于大鼠 2 号染色体上。
DOI: 10.1016/s0006-291x(88)80285-7
发表时间: 1988
影响因子: 3.1
作者:
Hendy,GN;Sakaguchi,AY;Yasuda,T;Weber,DK;Wang,LM;Yoshida,MC;Banville,D;Goltzman,D
通讯作者: Goltzman,D