Microglia and Their Promising Role in Ischemic Brain Injuries: An Update
Microglia and Their Promising Role in Ischemic Brain Injuries: An Update
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小胶质细胞及其在缺血性脑损伤中的潜在作用:最新进展
DOI:
10.3389/fncel.2020.00211
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发表时间:
2020-07
影响因子:
5.3
通讯作者:
Qu Yi
中科院分区:
文献类型:
--
作者:
Yu Luting;Su Xiaojuan;Li Shiping;Zhao Fengyan;Mu Dezhi;Qu Yi
Ischemic brain injuries are common diseases with high morbidity, disability, and mortality rates, which have significant impacts on human health and life. Microglia are resident cells of the central nervous system (CNS). The inflammatory responses mediated by microglia play an important role in the occurrence and development of ischemic brain injuries. This article summarizes the activation, polarization, depletion, and repopulation of microglia after ischemic brain injuries, proposing new treatment strategies for such injuries through the modulation of microglial function.
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