EcoCyc: a comprehensive database of Escherichia coli biology.

EcoCyc: a comprehensive database of Escherichia coli biology.
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DOI:
10.1093/nar/gkq1143
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发表时间:
2011-01
影响因子:
14.9
通讯作者:
Karp PD
Karp PD
中科院分区:
生物学2区
文献类型:
--
作者:
Keseler IM;Collado-Vides J;Santos-Zavaleta A;Peralta-Gil M;Gama-Castro S;Muñiz-Rascado L;Bonavides-Martinez C;Paley S;Krummenacker M;Altman T;Kaipa P;Spaulding A;Pacheco J;Latendresse M;Fulcher C;Sarker M;Shearer AG;Mackie A;Paulsen I;Gunsalus RP;Karp PD

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Ecocyc(http://ecocyc.org)是大肠杆菌K-12 MG1655的综合模型生物数据库。从科学文献中,Ecocyc捕获了各个大肠杆菌基因产品的功能。它们在转录,转录后和蛋白质水平上的调节;他们的组织进入操纵子,复合体和途径。 Ecocyc用户可以多种方式搜索和浏览信息。对Ecocyc Web界面的最新改进包括组合基因/蛋白质页和调节摘要图,显示了所有已知的调节输入对基因表达和蛋白质活性的图形概述。信号转导途径的图形表示已更新,并通过新功能增强了细胞和调节概述。正在开发一种使用Ecocyc的专业大学教学资源。
EcoCyc (http://EcoCyc.org) is a comprehensive model organism database for Escherichia coli K-12 MG1655. From the scientific literature, EcoCyc captures the functions of individual E. coli gene products; their regulation at the transcriptional, post-transcriptional and protein level; and their organization into operons, complexes and pathways. EcoCyc users can search and browse the information in multiple ways. Recent improvements to the EcoCyc Web interface include combined gene/protein pages and a Regulation Summary Diagram displaying a graphical overview of all known regulatory inputs to gene expression and protein activity. The graphical representation of signal transduction pathways has been updated, and the cellular and regulatory overviews were enhanced with new functionality. A specialized undergraduate teaching resource using EcoCyc is being developed.
DOI: 10.1093/nar/gkp875
发表时间: 2010-01
影响因子: 14.9
作者:
Caspi R;Altman T;Dale JM;Dreher K;Fulcher CA;Gilham F;Kaipa P;Karthikeyan AS;Kothari A;Krummenacker M;Latendresse M;Mueller LA;Paley S;Popescu L;Pujar A;Shearer AG;Zhang P;Karp PD
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发表时间: 1997-04-15
期刊: EMBO JOURNAL
影响因子: 11.4
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发表时间: 2008-01
影响因子: 14.9
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影响因子: 10.5
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通讯作者: Stock AM