What does the Dementia Rating Scale-2 measure? The relationship of neuropsychological measures to DRS-2 total and subscale scores in non-demented individuals with Parkinson's disease.
What does the Dementia Rating Scale-2 measure? The relationship of neuropsychological measures to DRS-2 total and subscale scores in non-demented individuals with Parkinson's disease.
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DOI：
10.1080/13854046.2021.1999505
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发表时间：
2023-01
影响因子：
3.9
通讯作者：
Bowers, Dawn
中科院分区：
文献类型：
--
作者：
Lopez, Francesca, V;Kenney, Lauren E.;Ratajska, Adrianna;Jacobson, Charles E.;Bowers, Dawn
痴呆症评定量表-2(DRS-2)被运动障碍学会推荐用于评估帕金森病(PD)的整体认知。然而，关于DRS-2在多大程度上对应于帕金森病患者的传统神经认知域(即结构效度)，经验证据有限。因此，本研究旨在确定DRS-2在非痴呆性帕金森病患者样本中的结构效度。帕金森病患者(n=359，平均年龄=64.50±8.53，文化程度=14.97±2.73，病程=8.48±4.87，UPDRS第三部分运动评分=25.23±10.17)作为综合神经心理学评估的一部分完成了DRS-2，包括注意力/工作记忆、执行功能、语言、延迟回忆和视觉操作空间技能。采用自举、纠偏、Spearman-Rho‘s相关和等级线性回归检验DRS-2总分和分量表的结构效度。在DRS-2总分中，集合转换的快速测量、对字母和语义线索的快速单词生成以及简单的视觉操作技能是导致DRS-2总分差异的主要原因。大多数DRS-2分量表得分与理论上相关的神经心理测量结果显示出较弱的关系。DRS-2总分反映了一系列认知领域(即执行、语言和视觉操作)的损害，而DRS-2分量表的分数具有有限的结构效度。总而言之，DRS-2似乎除了筛查帕金森病患者的全局认知之外，并没有什么用处。
The Dementia Rating Scale-2 (DRS-2) is recommended for assessing global cognition in Parkinson’s disease (PD) by the Movement Disorder Society. However, empirical evidence is limited regarding the degree to which the DRS-2 corresponds to traditional neurocognitive domains (i.e., construct validity) in PD. Thus, this study aims to determine the construct validity of the DRS-2 in a non-demented sample of PD patients. Patients with PD (n = 359; mean age = 64.50 ± 8.53, education = 14.97 ± 2.73, disease duration = 8.48 ± 4.87, UPDRS Part III motor scale scores = 25.23 ± 10.17) completed the DRS-2 as part of a comprehensive neuropsychological assessment consisting of attention/working memory, executive function, language, delayed recall, and visuoperceptual-spatial skills. Bootstrapped bias-corrected Spearman rho’s correlations andhierarchical linear regressions were performed to examine construct validity of DRS-2 total and subscale scores. Speeded measures of set-shifting, rapid word generation to letter and semantic cues, and simple visuoperceptual skills largely accounted for variance in DRS-2 total scores. Most DRS-2 subscale scores showed weak relationships with theoretically related neuropsychological measures. DRS-2 total scores reflect impairment across a range of cognitive domains (i.e., executive, language, and visuoperception), while DRS-2 subscale scores have limited construct validity. Together, the DRS-2 does not appear to have utility beyond screening for global cognition in PD.
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影响因子：
9.5
作者：
Carlson, Kevin D.;Herdman, Andrew O.
通讯作者：
Herdman, Andrew O.
影响因子：
3.5
作者：
Hughes, TA;Ross, HF;Spokes, EGS
通讯作者：
Spokes, EGS
影响因子：
11
作者：
Aarsland, D;Litvan, I;Larsen, JP
通讯作者：
Larsen, JP
DOI：
10.1111/j.1532-5415.2000.tb06891.x
发表时间：
2000-08-01
影响因子：
6.3
作者：
Aarsland, D;Larsen, JP;Laake, K
通讯作者：
Laake, K
影响因子：
2.6
作者：
BOBHOLZ, JH;BRANDT, J
通讯作者：
BRANDT, J