Prospects and Opportunities for Microsystems and Microfluidic Devices in the Field of Otorhinolaryngology.

Prospects and Opportunities for Microsystems and Microfluidic Devices in the Field of Otorhinolaryngology.
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耳鼻喉科领域中微系统和微流控装置的前景与机遇

DOI:
10.21053/ceo.2020.00626
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发表时间:
2021-03
影响因子:
3
通讯作者:
Revzin A
Revzin A
中科院分区:
医学2区
文献类型:
--
作者:
Hwang SH;Gonzalez-Suarez AM;Stybayeva G;Revzin A

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微流体系统可以用于以其他流体处理方法不可能的方式控制皮升至微升体积。近年来,微流体领域发展迅速,微流体设备提供了影响生物学和医学的可能性。填充有人类细胞的微流体装置具有在三维微环境中模拟组织和器官的生理功能的潜力,并且能够研究人类疾病的机制、药物发现和个性化医疗的实践。在耳鼻喉科领域,已经引入了各种类型的微流体系统来研究器官生理学、诊断疾病和评估治疗效果。因此,微流体技术可以在耳鼻喉科的各个层面实施。本文旨在促进对微流控特性的理解,并介绍近年来微流控相关器件在耳鼻咽喉科领域的应用。
Microfluidic systems can be used to control picoliter to microliter volumes in ways not possible with other methods of fluid handling. In recent years, the field of microfluidics has grown rapidly, with microfluidic devices offering possibilities to impact biology and medicine. Microfluidic devices populated with human cells have the potential to mimic the physiological functions of tissues and organs in a three-dimensional microenvironment and enable the study of mechanisms of human diseases, drug discovery and the practice of personalized medicine. In the field of otorhinolaryngology, various types of microfluidic systems have already been introduced to study organ physiology, diagnose diseases, and evaluate therapeutic efficacy. Therefore, microfluidic technologies can be implemented at all levels of otorhinolaryngology. This review is intended to promote understanding of microfluidic properties and introduce the recent literature on application of microfluidic-related devices in the field of otorhinolaryngology.
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