Smoking among morbidly obese patients.
Smoking among morbidly obese patients.
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DOI：
10.1186/1471-2466-10-61
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发表时间：
2010-11-24
影响因子：
3.1
通讯作者：
Chatkin JM
中科院分区：
文献类型：
--
作者：
Chatkin R;Mottin CC;Chatkin JM
与不吸烟者相比，吸烟者的体重指数（BMI）通常较低。然而，这种关系尚未在肥胖和病态肥胖患者中得到充分研究。本研究的目的是评估肥胖和病态肥胖受试者中吸烟与BMI之间的关系。在病例对照研究设计中，招募了1022名年龄在18-65岁之间的男女个体，并根据其吸烟状况（吸烟者、戒烟者和非吸烟者）和根据BMI（正常体重、超重、肥胖和病态肥胖）的营养状态进行分组。四个BMI组在吸烟状况方面没有显著差异。然而，与正常体重个体相比，超重、肥胖和病态肥胖受试者中吸烟者的频率更高（p = 0.078）。在逻辑回归分析中，校正潜在混杂因素后，与正常体重个体相比，病态肥胖受试者吸烟的校正OR为2.25（95%CI，1.52-3.34; p < 0.001）。在这个样本中，当体重正常的受试者的吸烟频率随着BMI的增加而减少时，这种趋势在超重、肥胖和病态肥胖患者中逆转。在后一组中，吸烟者的患病率明显高于其他组。病态肥胖患者成为吸烟者的风险增加2倍。我们推测，这些发现可能是各种重叠风险行为的结果，因为这些患者通常身体活动较少，更喜欢不太健康的饮食，除了与他们的同行相比有更多的酒精摄入量。这些发现的外部有效性必须得到证实。
Smokers usually have a lower Body Mass Index (BMI) when compared to non-smokers. Such a relationship, however, has not been fully studied in obese and morbidly obese patients. The objective of this study was to evaluate the relationship between smoking and BMI among obese and morbidly obese subjects. In a case-control study design, 1022 individuals of both genders, 18-65 years of age, were recruited and grouped according to their smoking status (smokers, ex-smokers, and non-smokers) and nutritional state according to BMI (normal weight, overweight, obese, and morbidly obese). No significant differences were detected in the four BMI groups with respect to smoking status. However, there was a trend towards a higher frequency of smokers among the overweight, obese, and morbidly obese subjects compared to normal weight individuals (p = 0.078). In a logistic regression, after adjusting for potential confounders, morbidly obese subjects had an adjusted OR of 2.25 (95% CI, 1.52-3.34; p < 0.001) to be a smoker when compared to normal weight individuals. In this sample, while the frequency of smokers diminished in normal weight subjects as the BMI increased, such a trend was reversed in overweight, obese, and morbidly obese patients. In the latter group, the prevalence of smokers was significantly higher compared to the other groups. A patient with morbid obesity had a 2-fold increased risk of becoming a smoker. We speculate that these finding could be a consequence of various overlapping risk behaviors because these patients also are generally less physically active and prefer a less healthy diet, in addition to having a greater alcohol intake in relation to their counterparts. The external validity of these findings must be confirmed.
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影响因子：
4.4
作者：
Borrelli, B;Mermelstein, R
通讯作者：
Mermelstein, R
影响因子：
4.9
作者：
Bamia, C;Trichopoulou, A;Trichopoulos, D
通讯作者：
Trichopoulos, D
影响因子：
4.9
作者：
Nielsen, TL;Wraae, K;Hagen, C
通讯作者：
Hagen, C
影响因子：
2.2
作者：
Komiya, H;Mori, Y;Tajima, N
通讯作者：
Tajima, N
影响因子：
158.5
作者：
FLEGAL, KM;TROIANO, RP;CAMPBELL, SM
通讯作者：
CAMPBELL, SM