Combining endocardial mapping and electrocardiographic imaging (ECGI) for improving PVC localization: A feasibility study.
Combining endocardial mapping and electrocardiographic imaging (ECGI) for improving PVC localization: A feasibility study.
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DOI：
10.1016/j.jelectrocard.2021.08.013
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发表时间：
2021-11
影响因子：
1.3
通讯作者：
MacLeod, Rob S.
中科院分区：
文献类型：
--
作者：
Good, Wilson W.;Zenger, Brian;Bergquist, Jake A.;Rupp, Lindsay C.;Gillette, Karli;Angel, Nathan;Chou, Derrick;Plank, Gernot;MacLeod, Rob S.
心脏激动波阵面的准确重建对于心律失常的临床诊断、管理和治疗至关重要。此外，由于电标测仅在内膜表面进行，因此长期以来不可能重建壁内心肌的激活曲线。心电图成像（ECGI）的最新进展使心内膜和心外膜激动标测成为可能。我们提出了一种新的方法，使用心内膜和心外膜映射的组合方法来重建壁内激动时间。实施并确认心外膜/心内膜组合壁内激动时间重建技术。我们使用了11个模拟的心室激动起搏从整个心肌壁的网站，并提取心内膜和心外膜激动地图在近似的临床分辨率。从这些地图，我们内插激活时间通过心肌使用薄板样条径向基函数。我们使用激活时间的均方根误差（RMSE）和地面真实值1 ms内的节点百分比来评估激活时间重建精度。重建的壁内激活时间显示RMSE和1 ms内的节点百分比分别为3 ms和70%。在最坏的情况下，RMSE和节点的百分比分别为4 ms和60%。我们发现，一个简单而有效的临床心内膜和心外膜激动地图的组合可以准确地重建壁内波前。此外，我们表明，这种方法提供了强大的重建跨多个壁内刺激部位。
Accurate reconstruction of cardiac activation wavefronts is crucial for clinical diagnosis, management, and treatment of cardiac arrhythmias. Furthermore, reconstruction of activation profiles within the intramural myocardium has long been impossible because electrical mapping was only performed on the endocardial surface. Recent advancements in electrocardiographic imaging (ECGI) have made endocardial and epicardial activation mapping possible. We propose a novel approach to use both endocardial and epicardial mapping in a combined approach to reconstruct intramural activation times. To implement and validate a combined epicardial/endocardial intramural activation time reconstruction technique. We used 11 simulations of ventricular activation paced from sites throughout myocardial wall and extracted endocardial and epicardial activation maps at approximate clinical resolution. From these maps, we interpolated the activation times through the myocardium using thin-plate-spline radial basis functions. We evaluated activation time reconstruction accuracy using root-mean-squared error (RMSE) of activation times and the percent of nodes within 1 ms of the ground truth. Reconstructed intramural activation times showed an RMSE and percentage of nodes within 1 ms of the ground truth simulations of 3 ms and 70%, respectively. In the worst case, the RMSE and percentage of nodes were 4 ms and 60%, respectively. We showed that a simple, yet effective combination of clinical endocardial and epicardial activation maps can accurately reconstruct intramural wavefronts. Furthermore, we showed that this approach provided robust reconstructions across multiple intramural stimulation sites.
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影响因子：
10.9
作者：
Gillette, Karli;Gsell, Matthias A. F.;Plank, Gernot
通讯作者：
Plank, Gernot
影响因子：
82.9
作者：
Ramanathan, C;Ghanem, RN;Rudy, Y
通讯作者：
Rudy, Y
影响因子：
8.4
作者：
Hohmann, Stephan;Rettmann, Maryam E.;Packer, Douglas L.
通讯作者：
Packer, Douglas L.
影响因子：
3.2
作者：
Zenger B;Good WW;Bergquist JA;Burton BM;Tate JD;Berkenbile L;Sharma V;MacLeod RS
通讯作者：
MacLeod RS
影响因子：
4
作者：
Cluitmans M;Brooks DH;MacLeod R;Dössel O;Guillem MS;van Dam PM;Svehlikova J;He B;Sapp J;Wang L;Bear L
通讯作者：
Bear L