Pre- Versus Postmeal Sedentary Duration—Impact on Postprandial Glucose in Older Adults With Overweight or Obesity
Pre- Versus Postmeal Sedentary Duration—Impact on Postprandial Glucose in Older Adults With Overweight or Obesity
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餐前与餐后久坐时间对超重或肥胖老年人餐后血糖的影响
DOI：
10.1123/jmpb.2023-0032
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发表时间：
2024
期刊：
影响因子：
--
通讯作者：
Lyden, Kate
中科院分区：
文献类型：
--
作者：
Chun, Elizabeth;Gaynanova, Irina;Melanson, Edward L.;Lyden, Kate
简介：减少久坐时间与改善餐后血糖调节有关。然而，目前尚不清楚久坐行为的时机(即餐前和餐后)是否会对超重或肥胖的老年人的餐后血糖产生不同的影响。方法：在这项二次分析中，超重和肥胖的老年人(≥65岁)在四个不同的场合连续四天在现实环境中佩戴连续血糖监测仪和久坐行为监测仪。在每个4天的测量期内，参与者遵循标准的优卡饮食，并在日记中记录用餐时间。使用传感器和日记时间戳融合了血糖、久坐行为和膳食摄入量数据。结果：餐前久坐时间与餐前血糖峰值升高(ΔG)和餐后1小时血糖峰值恢复的百分比(%基线恢复；p<； .05)显著相关，餐前久坐时间越长，ΔG越大，基线恢复百分比越小。餐后久坐时间与餐后至血糖峰值的时间显著相关(ΔT；p<； .05)，餐后久坐时间越长，达到峰值的时间越长。结论：餐前和餐后久坐行为不同地影响超重或肥胖老年人的餐后血糖反应，提示久坐行为减少的时机可能对长期血糖控制起到影响作用。
Introduction: Reducing sedentary time is associated with improved postprandial glucose regulation. However, it is not known if the timing of sedentary behavior (i.e., pre- vs. postmeal) differentially impacts postprandial glucose in older adults with overweight or obesity.Methods: In this secondary analysis, older adults (≥65 years) with overweight and obesity (body mass index ≥ 25 kg/m2) wore a continuous glucose monitor and a sedentary behavior monitor continuously in their real-world environments for four consecutive days on four separate occasions. Throughout each 4-day measurement period, participants followed a standardized eucaloric diet and recorded mealtimes in a diary. Glucose, sedentary behavior, and meal intake data were fused using sensor and diary timestamps. Mixed-effect linear regression models were used to evaluate the impact of sedentary timing relative to meal intake.Results: Premeal sedentary time was significantly associated with both the increase from premeal glucose to the postmeal peak (ΔG) and the percent of premeal glucose increase that was recovered 1-hr postmeal glucose peak (%Baseline Recovery;p< .05), with higher levels of premeal sedentary time leading to both a larger ΔGand a smaller %Baseline Recovery. Postmeal sedentary time was significantly associated with the time from meal intake to glucose peak (ΔT;p< .05), with higher levels of postmeal sedentary time leading to a longer time to peak.Conclusions: Pre- versus postmeal sedentary behavior differentially impacts postprandial glucose response in older adults with overweight or obesity, suggesting that the timing of sedentary behavior reductions might play an influential role on long-term glycemic control.
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影响因子：
24
作者：
Chomistek, Andrea K.;Manson, JoAnn E.;Stefanick, Marcia L.;Lu, Bing;Sands-Lincoln, Megan;Going, Scott B.;Garcia, Lorena;Allison, Matthew A.;Sims, Stacy T.;LaMonte, Michael J.;Johnson, Karen C.;Eaton, Charles B.
通讯作者：
Eaton, Charles B.
影响因子：
1.9
作者：
Hu, FB
通讯作者：
Hu, FB
DOI：
--
发表时间：
2015-10
期刊：
--
影响因子：
--
作者：
Douglas M. Bates;M. Maechler;Ben Bolker;Steven C. Walker
通讯作者：
Douglas M. Bates;M. Maechler;Ben Bolker;Steven C. Walker
尽量减少所有年龄段的久坐行为，以实现健康老龄化
影响因子：
--
作者：
S. Chastin;D. Skelton
通讯作者：
D. Skelton
影响因子：
18.4
作者：
Bull FC;Al-Ansari SS;Biddle S;Borodulin K;Buman MP;Cardon G;Carty C;Chaput JP;Chastin S;Chou R;Dempsey PC;DiPietro L;Ekelund U;Firth J;Friedenreich CM;Garcia L;Gichu M;Jago R;Katzmarzyk PT;Lambert E;Leitzmann M;Milton K;Ortega FB;Ranasinghe C;Stamatakis E;Tiedemann A;Troiano RP;van der Ploeg HP;Wari V;Willumsen JF
通讯作者：
Willumsen JF