Volumetric navigators for real-time motion correction in diffusion tensor imaging.
Volumetric navigators for real-time motion correction in diffusion tensor imaging.
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DOI：
10.1002/mrm.23314
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发表时间：
2012-10
影响因子：
3.3
通讯作者：
van der Kouwe, Andre J. W.
中科院分区：
文献类型：
--
作者：
Alhamud, A.;Tisdall, M. Dylan;Hess, Aaron T.;Hasan, Khader M.;Meintjes, Ernesta M.;van der Kouwe, Andre J. W.
关键词：
利用光学系统、DW-PACE或自由感应衰减（FID）导航仪的前瞻性运动校正方法最近被应用于DTI中的运动校正。这些方法都有一定的局限性和缺陷。本文描述了一种使用3D-EPI导航器的新技术，其对比度与b值无关，可以在扩散加权图像中执行前瞻性运动校正，而无需重新获取运动发生期间的体积，除非运动超过了一些预设的阈值。采用标准扩散序列和导航扩散序列获取水幻影和人脑数据，分析分数各向异性（FA）和平均扩散率（MD）的平均直方图和全脑直方图（WBH）。结果表明，导航器的加入对扩散序列没有影响。随着头部运动，WBH-FA向低各向异性转移，平均FA和FA直方图峰值位置均显著降低（p<0.01），而WBH-MD向高扩散性转移，平均MD显著增加（p<0.01），即使在回顾性运动校正后也是如此。这些平均值和直方图形状的变化在使用导航序列获得的预期运动校正数据中得到了实质性的恢复。
Prospective motion correction methods utilizing an optical system, DW-PACE or a free induction decay (FID) navigator, have recently been applied to correct for motion in DTI. These methods have some limitations and drawbacks. This paper describes a novel technique using a 3D-EPI navigator, of which the contrast is independent of the b-value, to perform prospective motion correction in diffusion weighted images, without having to reacquire volumes during which motion occurred, unless motion exceeded some pre-set thresholds. Water phantom and human brain data were acquired using the standard and navigated diffusion sequences, and the mean and whole brain histogram (WBH) of the fractional anisotropy (FA) and mean diffusivity (MD) were analysed. Our results show that adding the navigator does not influence the diffusion sequence. With head motion, the WBH-FA shows a shift toward lower anisotropy with a significant decrease in both the mean FA and the FA histogram peak location (p<0.01), while the WBH-MD shows a shift toward higher diffusivity with a significant increase in the mean MD (p<0.01), even after retrospective motion correction. These changes in the mean and the shape of the histograms are recovered substantially in the prospective motion corrected data acquired using the navigated sequence.
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影响因子：
16.2
作者：
Tuch, DS;Reese, TG;Wedeen, VJ
通讯作者：
Wedeen, VJ
影响因子：
2.9
作者：
Hasan KM;Iftikhar A;Kamali A;Kramer LA;Ashtari M;Cirino PT;Papanicolaou AC;Fletcher JM;Ewing-Cobbs L
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影响因子：
3.3
作者：
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Wedeen, VJ
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作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
Mascalchi, M.