Fungal Strategies to Evade the Host Immune Recognition.
Fungal Strategies to Evade the Host Immune Recognition.
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DOI:
10.3390/jof3040051
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发表时间:
2017-09-23
期刊:
影响因子:
--
通讯作者:
Mora-Montes HM
中科院分区:
文献类型:
--
作者:
Hernández-Chávez MJ;Pérez-García LA;Niño-Vega GA;Mora-Montes HM
The recognition of fungal cells by the host immune system is key during the establishment of a protective anti-fungal response. Even though the immune system has evolved a vast number of processes to control these organisms, they have developed strategies to fight back, avoiding the proper recognition by immune components and thus interfering with the host protective mechanisms. Therefore, the strategies to evade the immune system are as important as the virulence factors and attributes that damage the host tissues and cells. Here, we performed a thorough revision of the main fungal tactics to escape from the host immunosurveillance processes. These include the composition and organization of the cell wall, the fungal capsule, the formation of titan cells, biofilms, and asteroid bodies; the ability to undergo dimorphism; and the escape from nutritional immunity, extracellular traps, phagocytosis, and the action of humoral immune effectors.
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