Imaging characteristics of tenosynovial giant cell tumors on (18)F-fluorodeoxyglucose positron emission tomography/computed tomography: a retrospective observational study.
Imaging characteristics of tenosynovial giant cell tumors on (18)F-fluorodeoxyglucose positron emission tomography/computed tomography: a retrospective observational study.
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DOI：
10.1186/s12891-023-06730-1
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发表时间：
2023-07-19
影响因子：
2.3
通讯作者：
中科院分区：
文献类型：
--
作者：
18F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（18F-FDG-PET/CT）可用于评估恶性肿瘤的位置、转移、分期和复发。腱鞘巨细胞瘤（TSGCT）是一种良性肿瘤；然而，一些研究报告 TSGCT 对 FDG 的吸收率较高。很少有研究报道使用 18F-FDG-PET/CT 对 TSGCT 进行详细评估。当前研究的目的是评估图像特征和位置，特别是在可能的情况下，无论是否存在 18F-FDG-PET/CT 中膝关节 TSGCT 可能发生的关节外侵犯。我们回顾性分析了通过活检或手术标本病理诊断的 TSGCT 患者。此外，我们评估了关节外侵犯的弥漫性 TSGCT 和膝关节内定位的 TSGCT 之间最大标准化摄取值 (SUVmax) 的差异。该研究由 20 名 TSGCT 患者组成。 TSGCT 的平均 SUVmax 为 12.0±6.50。 5 例 TSGCT 患者发生于膝关节外，有关节外侵犯，6 例 TSGCT 发生于关节内。关节外侵犯和关节内定位的 TSGCT 的平均 SUVmax 分别为 14.3±6.00 和 5.94±3.89。关节外侵犯的 TSGCT 的 SUVmax 显着高于关节内定位的 TSGCT (p<<0.05)。 TSGCT 显示高 FDG 吸收。此外，关节外侵犯的弥漫性 TSGCT 的 SUVmax 高于关节内局限性 TSGCT；这可能反映了其局部侵略性。在线版本包含可在 10.1186/s12891-023-06730-1 获取的补充材料。
18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) is useful for assessing location, metastasis, staging, and recurrence of malignant tumors. Tenosynovial giant cell tumor (TSGCT) is a benign tumor; however, some studies have reported that TSGCTs have a high uptake of FDG. Few studies have reported on the detailed evaluation of TSGCT using 18F-FDG-PET/CT. The purpose of the current study is to evaluate the image characteristics and locations, particularly where possible, with or without, extra-articular invasion from TSGCT of the knee in 18F-FDG-PET/CT could occur. We retrospectively reviewed the patients with TSGCT who were diagnosed pathologically either by biopsy or surgical specimen. Furthermore, we evaluated the difference of the maximum standardized uptake value (SUVmax) between diffused TSGCT with extra-articular invasion and TSGCT with intra-articular localization in the knee. The study consisted of 20 patients with TSGCT. The mean SUVmax of TSGCT was 12.0 ± 6.50. There were five patients with TSGCT arising in the knee with extra-articular invasion and six with TSGCT with intra-articular localization. The mean SUVmax of TSGCT with extra-articular invasion and those with intra-articular localization were 14.3 ± 6.00 and 5.94 ± 3.89, respectively. TSGCT with extra-articular invasion had significantly higher SUVmax than TSGCT with intra-articular localization (p < 0.05). TSGCT revealed high FDG uptake. Furthermore, SUVmax was higher in diffused TSGCT with extra-articular invasion than in intra-articular localized TSGCT; this may reflect its local aggressiveness. The online version contains supplementary material available at 10.1186/s12891-023-06730-1.
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影响因子：
10.6
作者：
Broski, Stephen M.;Murdoch, Nathan M.;Wenger, Doris E.
通讯作者：
Wenger, Doris E.
DOI：
10.1302/0301-620x.82b5.9824
发表时间：
2000-07-01
影响因子：
--
作者：
Watanabe, H;Shinozaki, T;Takagishi, K
通讯作者：
Takagishi, K
DOI：
10.1007/s00259-015-3242-z
发表时间：
2016-05
影响因子：
9.1
作者：
Etchebehere, Elba C.;Hobbs, Brian P.;Milton, Denai R.;Malawi, Osama;Patel, Shreyaskumar;Benjamin, Robert S.;Macapinlac, Homer A.
通讯作者：
Macapinlac, Homer A.
影响因子：
2.3
作者：
Takeuchi A;Yamamoto N;Hayashi K;Miwa S;Takahira M;Fukui K;Oikawa T;Tsuchiya H
通讯作者：
Tsuchiya H
影响因子：
3.5
作者：
Sbaraglia M;Bellan E;Dei Tos AP
通讯作者：
Dei Tos AP