Decreasing Incidence of Skin and Soft Tissue Infections With a Seasonal Pattern at an Academic Medical Center, 2006-2014.

Decreasing Incidence of Skin and Soft Tissue Infections With a Seasonal Pattern at an Academic Medical Center, 2006-2014.
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DOI:
10.1093/ofid/ofw179
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发表时间:
2016-10
影响因子:
4.2
通讯作者:
David MZ
David MZ
中科院分区:
医学3区
文献类型:
--
作者:
Morgan E;Daum RS;David MZ

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芝加哥大学医学院的SSTI发病率随季节变化在儿童和成人中显著下降,在夏季达到高峰。这表明2000年后美国SSTI发病率大幅上升的趋势发生逆转。背景2000年后,随着USA 300耐甲氧西林金黄色葡萄球菌的出现,美国皮肤和软组织感染(SSTI)的发病率急剧上升。 我们研究了芝加哥大学医学院(UCM)2006-2014年SSTI发病率的趋势。 方法:收集2006年1月1日至2014年3月31日期间在UCM就诊的患者资料,采用国际疾病分类第九修订版编码的SSTI诊断。 按季度和年度计算每1000次遭遇的发病密度。根据住院、门诊和急诊(艾德)就诊以及年龄组、性别和种族对就诊进行分层。Poisson回归用于评估随时间的变化。 结果:在2006-2014年,收集了31869名受试者中38201例SSTI相关遭遇的数据。 在UCM治疗的所有患者中,2006-2013年期间SSTI的发病率每年下降1%,总体下降16%。在住院病人中,(率比[RR] = 0.97; 95%置信区间[CI],0.96 - 0.98),艾德患者(RR = 0.98; 95%CI,0.97 - 0.98)、成人(RR = 0.98; 95%CI,0.97 - 0.98)、儿童(RR = 0.96; 95%CI,0.95 - 0.97)和非裔美国人(RR = 0.99; 95%CI,0.98 - 0.99)。有一个年度的季节性趋势,发病高峰发生在夏末。 结论:UCM的儿童和成人SSTI发病率随季节变化而降低,在夏季达到高峰。 这表明2000年后美国SSTI发病率大幅增加的趋势发生了逆转。
The incidence of SSTIs at University of Chicago Medicine decreased significantly in children and adults with seasonal variation, peaking during the summer months. This suggests a reversal of the massive increase in SSTI incidence after 2000 in the U.S. Background. The incidence of skin and soft tissue infections (SSTIs) in the United States increased sharply after 2000 with the emergence of USA300 methicillin-resistant Staphylococcus aureus. We examined trends in SSTI incidence in 2006–2014 at the University of Chicago Medicine (UCM). Methods. Data were obtained for patient encounters at UCM with an International Classification of Diseases, Ninth Revision-coded SSTI diagnosis between January 1, 2006 and March 31, 2014. Incidence density was calculated per 1000 encounters by quarter and year. Encounters were stratified by inpatient, outpatient clinic and emergency department (ED) encounters and by age group, gender, and race. Poisson regression was used to assess change over time. Results. In 2006–2014, data were collected for 38 201 SSTI-associated encounters among 31 869 subjects. Among all patients treated at UCM, there was a decrease of 1% per year in the incidence of SSTIs during 2006–2013, with an overall decrease of 16%. There was a significant decrease in SSTI-related encounters among inpatients (rate ratio [RR] = 0.97; 95% confidence interval [CI], .96–.98), ED patients (RR = 0.98; 95% CI, .97–.98), adults (RR = 0.98; 95% CI, .97–.98), children (RR = 0.96; 95% CI, .95–.97), and African Americans (RR = 0.99; 95% CI, .98–.99). There was an annual seasonal trend, with the peak incidence occurring during the late summer. Conclusions. The incidence of SSTIs at UCM decreased in children and adults with seasonal variation, peaking during the summer months. This suggests a reversal of the massive increase in SSTI incidence in the United States after 2000.
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