Obstructive sleep apnea in pregnancy: reliability of prevalence and prediction estimates.
Obstructive sleep apnea in pregnancy: reliability of prevalence and prediction estimates.
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DOI：
10.1038/jp.2014.48
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发表时间：
2014-08
影响因子：
2.9
通讯作者：
Aagaard, K. M.
中科院分区：
文献类型：
--
作者：
Antony, K. M.;Agrawal, A.;Arndt, M. E.;Murphy, A. M.;Alapat, P. M.;Guntupalli, K. K.;Aagaard, K. M.
本研究旨在确定两种筛查量表对妊娠期阻塞性睡眠呼吸暂停（OSA）的有效性，并确定OSA在妊娠期的患病率。在这项前瞻性观察性研究中，使用了两种筛选量表。筛选阳性受试者转诊接受诊断性多导睡眠图（PSG）;如果入院接受产前护理，筛选阳性受试者接受使用3型器械（T3 D）的改良研究。1509例受试者接受了OSA筛查; 58例完成了诊断测试。这两项测量都不是T3 D或PSG确定的OSA的可靠诊断工具（检出率分别为10.3%和18.0%）。在接受PSG或T3 D检测的筛查阳性受试者中，15.5%最终符合“金标准”OSA诊断标准，估计点患病率为4.9%。在这项前瞻性试验中，BQ或ESS筛查阳性对孕妇OSA的预测性较差，并与高假转诊率相关。
We sought to ascertain the validity of two screening scales for obstructive sleep apnea (OSA) in pregnancy and to establish the prevalence of OSA in pregnancy. In this prospective observational study, two screening scales were administered. Screen positive subjects were referred for diagnostic polysomnography (PSG); if admitted for antepartum care, screen positive subjects underwent a modified study with a type 3 device (T3D). 1509 subjects underwent OSA screening; 58 completed diagnostic testing. Neither measure was a reliable diagnostic tool for OSA as determined by T3D or PSG (detection rates of 10.3% and 18.0%, respectively). Among screen positive subjects undergoing PSG or T3D testing, 15.5% ultimately met ‘gold standard’ OSA diagnostic criteria for an estimated point prevalence of 4.9%. In this prospective trial, screening positive on the BQ or ESS was poorly predictive of OSA among gravidae and was associated with a high false referral rate.
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