In vivo proton nuclear magnetic resonance imaging and spectroscopy studies of halocarbon‐induced liver damage
In vivo proton nuclear magnetic resonance imaging and spectroscopy studies of halocarbon‐induced liver damage
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卤烃引起的肝损伤的体内质子核磁共振成像和光谱学研究
DOI：
10.1002/mrm.1910090208
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发表时间：
1989
影响因子：
3.3
通讯作者：
D. Foxall
中科院分区：
文献类型：
--
作者：
M. Brauer;R. Towner;Ian Renaud;E. Janzen;D. Foxall
利用质子磁共振成像和局部核磁共振波谱对大鼠肝脏进行了原位研究。在成像和局部光谱研究中均使用呼吸门控来控制大鼠在呼吸期间上腹部的运动。四氯化碳，溴三氯甲烷，或氟烷，局部区域的高质子信号强度后，在肝脏的NMR图像观察。来自这些区域内的局部（VOSY）质子NMR谱表明，信号强度的增加是由于水共振的较长T2弛豫时间，表明组织损伤区域中的急性水肿。出版社：Academic Press，Inc.
Proton magnetic resonance imaging and localized NMR spectroscopy were used to study the rat liver in situ. Respiratory gating was used in both the imaging and the localized spectroscopy studies to control for the movement of the upper abdomen of the rat during breathing. After administration of carbon tetrachloride, bromotrichloromethane, or halothane, localized regions of high proton signal intensity were observed in the NMR images of the liver. Localized (VOSY) proton NMR spectra from within these regions indicated that the increase in a signal intensity was due to a longer T2 relaxation time for the water resonance, indicating acute edema in the region of tissue damage. © 1989 Academic Press, Inc.
影响因子：
19.7
作者：
Stark,DD;Bass,NM;Moss,AA;Bacon,BR;McKerrow,JH;Cann,CE;Brito,A;Goldberg,HI
通讯作者：
Goldberg,HI
DOI：
10.1016/0748-5514(85)90026-1
发表时间：
1985-01-01
期刊：
Journal of Free Radicals in Biology and Medicine
影响因子：
--
作者：
BRATTIN W J;GLENDE E A JR;RECKNAGEL R O
通讯作者：
RECKNAGEL R O
质子化学位移成像：使用体内脂肪肝模型评估其临床潜力。
影响因子：
19.7
作者：
Rosen,BR;Carter,EA;Pykett,IL;Buchbinder,BR;Brady,TJ
通讯作者：
Brady,TJ