Hydromechanical Structure of the Cochlea Supports the Backward Traveling Wave in the Cochlea In Vivo.
Hydromechanical Structure of the Cochlea Supports the Backward Traveling Wave in the Cochlea In Vivo.
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耳蜗的流体力学结构支持体内耳蜗中的向后行波
DOI：
10.1155/2018/7502648
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发表时间：
2018
影响因子：
3.1
通讯作者：
Nuttall A
中科院分区：
文献类型：
--
作者：
Chen F;Zha D;Yang X;Hubbard A;Nuttall A
前向传播耳声发射（OAE）引起基底膜振动的发现在耳蜗力学领域引起了严重的争论。传统理论预测OAE将通过基底膜上的后向行波传播到耳道，而反对者理论提出OAE将通过压缩波到达耳道。后向行波理论的基本现象虽然被大多数人所接受，但尚未得到实验证明。在这项研究中，第一次，我们显示了后向行波通过测量相位谱的基底膜振动在多个纵向位置的耳蜗的基回。在耳蜗分区上创建具有唯一和精确位置的局部振动源，以避免大多数先前研究中振动源的模糊性。我们还测量了机械耳蜗模型不同位置的振动模式。测量数据的时域序列显示了一种缓慢的后向行波模式。除了波的传播研究，传输线的数学模型被用来解释为什么没有tonotopicity被观察到的向后行波。
The discovery that an apparent forward-propagating otoacoustic emission (OAE) induced basilar membrane vibration has created a serious debate in the field of cochlear mechanics. The traditional theory predicts that OAE will propagate to the ear canal via a backward traveling wave on the basilar membrane, while the opponent theory proposed that the OAE will reach the ear canal via a compression wave. Although accepted by most people, the basic phenomenon of the backward traveling wave theory has not been experimentally demonstrated. In this study, for the first time, we showed the backward traveling wave by measuring the phase spectra of the basilar membrane vibration at multiple longitudinal locations of the basal turn of the cochlea. A local vibration source with a unique and precise location on the cochlear partition was created to avoid the ambiguity of the vibration source in most previous studies. We also measured the vibration pattern at different places of a mechanical cochlear model. A slow backward traveling wave pattern was demonstrated by the time-domain sequence of the measured data. In addition to the wave propagation study, a transmission line mathematical model was used to interpret why no tonotopicity was observed in the backward traveling wave.
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影响因子：
2.5
作者：
Meenderink, Sebastiaan W. F.;van der Heijden, Marcel
通讯作者：
van der Heijden, Marcel
影响因子：
2.4
作者：
Ni, Guangjian;Elliott, Stephen J.
通讯作者：
Elliott, Stephen J.
影响因子：
2.4
作者：
Chen, FY;Cohen, HI;Hubbard, AE
通讯作者：
Hubbard, AE
影响因子：
2.4
作者：
de Boer, Egbert;Zheng, Jiefu;Nuttall, Alfred L.
通讯作者：
Nuttall, Alfred L.
影响因子：
3.4
作者：
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通讯作者：
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