Reframing the perception of outliers and negative data in translational research.
Reframing the perception of outliers and negative data in translational research.
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DOI:
10.1016/j.brainresbull.2022.11.020
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发表时间:
2023-01
影响因子:
3.8
通讯作者:
中科院分区:
文献类型:
--
作者:
Negative results can be a source of disappointment for scientists, yet their publication is needed for scientific progress, in particular for cutting-edge translational research of novel therapeutics. This manuscript is directed to scientists, junior and senior, that produce and review data for publication. It discusses the difference between ‘negative’ or ‘unexpected’ data and ‘useless’ data, re-evaluates the importance of the experimental design to generate valuable data and proposes strategies to work with and report negative results. Overall, it aims to reframe the perception of working with, reporting and reviewing unexpected data as an opportunity to provide rationale for innovative ideas, prevent the misuse of limited resources and, ultimately, strengthen the reputation of a scientist.
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影响因子:
8.8
作者:
Emborg ME;Liu Y;Xi J;Zhang X;Yin Y;Lu J;Joers V;Swanson C;Holden JE;Zhang SC
通讯作者:
Zhang SC
影响因子:
4.5
作者:
Mancinelli AM;Vichich JM;Zinnen AD;Hugon AM;Bondarenko V;Metzger JM;Simmons HA;Golos TG;Emborg ME
通讯作者:
Emborg ME
影响因子:
8.6
作者:
Kimmelman, Jonathan;London, Alex John;Ravina, Bernard;Ramsay, Tim;Bernstein, Mark;Fine, Alan;Stahnisch, Frank W.;Emborg, Marina Elena
通讯作者:
Emborg, Marina Elena
影响因子:
--
作者:
Percie du Sert N;Hurst V;Ahluwalia A;Alam S;Avey MT;Baker M;Browne WJ;Clark A;Cuthill IC;Dirnagl U;Emerson M;Garner P;Holgate ST;Howells DW;Karp NA;Lazic SE;Lidster K;MacCallum CJ;Macleod M;Pearl EJ;Petersen OH;Rawle F;Reynolds P;Rooney K;Sena ES;Silberberg SD;Steckler T;Würbel H
通讯作者:
Würbel H
影响因子:
3.3
作者:
Emborg ME;Zhang Z;Joers V;Brunner K;Bondarenko V;Ohshima S;Zhang SC
通讯作者:
Zhang SC