Trends in perivascular macrophages research from 1997 to 2021: A bibliometric analysis.

Trends in perivascular macrophages research from 1997 to 2021: A bibliometric analysis.
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DOI:
10.1111/cns.14034
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发表时间:
2023-03
影响因子:
5.5
通讯作者:
--
中科院分区:
医学1区
文献类型:
--
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血管周围巨噬细胞(PVM)在维持大脑的生理功能中发挥着关键作用。 PVM 功能障碍正在成为多种大脑疾病的重要机制。在这项工作中,我们利用基于 2021 年 10 月 27 日搜索术语“血管周围巨噬细胞”和“血管周围巨噬细胞”的文献计量分析,从 Web of Science (WoS) 核心数据库中分析了 PVM(尤其是大脑)的最新研究进展。可视化和协作分析由 Citespace (5.8 R3 mac) 进行。我们找到了 1997 年至 2021 年间发表的 PVM 领域的 2384 篇文章,我们选择这些文章进行分析。 PVMs涉及多个生理病理学领域,其中神经科学和神经病学、神经科学、免疫学、病理学、心血管系统和心脏病学报道最多。该研究重点关注中枢神经系统(CNS)、炎症、巨噬细胞或T细胞和疾病中的PVM,并重点关注其激活、氧化应激、血管紧张素II和胰岛素抵抗等相关基础研究。肿瘤相关巨噬细胞、肥胖、骨髓细胞和炎症是近年来引起越来越多关注的相对较新的关键词。哈佛大学、阿姆斯特丹自由大学在PVMs研究领域占据重要地位。与此同时,中国(北京大学、中山大学、上海交通大学、山东大学)的PVM研究正在兴起。聚类共被引分析显示,中枢神经系统PVMs及相关脑部疾病的机制是与PVMs相关的主要专业,而血管周围脂肪组织和血管疾病或肥胖中的PVMs是PVMs热点的另一大类。综上所述,PVM的研究不断深入,热点不断变化。 PVM 的未来研究可能会涉及多个学科的交叉。 1997 年至 2021 年血管周围巨噬细胞的 Citespace Reference 共被引分析网络(聚类视图)。该网络的模块度为 0.8446,平均轮廓得分为 0.9382。每个簇的标签显示在块旁边。簇的颜色显示了共被引链接发生的时间。红色表示引用年份较早,黄色表示引用时间较近。
Perivascular macrophages (PVMs) play pivotal roles in maintaining the physiological function of the brain. Dysfunction of PVMs is emerging as an important mechanism in various disease conditions in the brain. In this work, we analyzed recent research advances in PVMs, especially in the brain, from the Web of Science (WoS) core database using bibliometric analysis based on the search terms “perivascular macrophages” and “perivascular macrophage” on October 27, 2021. Visualization and collaboration analysis were performed by Citespace (5.8 R3 mac). We found 2384 articles published between 1997 and 2021 in the field of PVMs, which were selected for analysis. PVMs were involved in several physio‐pathological fields, in which Neurosciences and Neurology, Neuroscience, Immunology, Pathology, and Cardiovascular System and Cardiology were most reported. The research focuses on PVMs mainly in the central nervous system (CNS), inflammation, macrophage or T‐cell, and disease, and highlights the related basic research regarding its activation, oxidative stress, angiotensin II, and insulin resistance. Tumor‐associated macrophage, obesity, myeloid cell, and inflammation were relatively recent highlight keywords that attracted increasing attention in recent years. Harvard Univ, Vrije Univ Amsterdam, occupied important positions in the research field of PVMs. Meanwhile, PVM research in China (Peking Univ, Sun Yat Sen Univ, Shanghai Jiao Tong Univ, and Shandong Univ) is on the rise. Cluster co‐citation analysis revealed that the mechanisms of CNS PVMs and related brain diseases are major specialties associated with PVMs, while PVMs in perivascular adipose tissue and vascular diseases or obesity are another big category of PVMs hotspots. In conclusion, the research on PVMs continues to deepen, and the hotspots are constantly changing. Future studies of PVMs could have multiple disciplines intersecting. Citespace Reference co‐citation analysis network (Cluster View) in perivascular macrophages from 1997 to 2021. The network has a modularity of 0.8446 and an average silhouette score of 0.9382. The labels of each cluster are exhibited beside the blocks. The color of the clusters shows when the co‐citation links happened. The red color means the citing year is relatively early, and the yellow color indicates that the citation time is relatively recent.
DOI: 10.1007/s00109-017-1573-x
发表时间: 2017-11
期刊: Journal of molecular medicine (Berlin, Germany)
影响因子: --
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