Retinal ganglion cell maps in the brain: implications for visual processing.

Retinal ganglion cell maps in the brain: implications for visual processing.
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DOI:
10.1016/j.conb.2013.08.006
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发表时间:
2014-02
影响因子:
5.7
通讯作者:
Huberman AD
Huberman AD
中科院分区:
医学2区
文献类型:
--
作者:
Dhande OS;Huberman AD

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大脑对视觉世界内容的了解都是由视网膜神经节细胞(RGC)的尖峰活动建立的。作为眼睛的输出神经元,RGC包括约20种不同的亚型,每种亚型对视觉场景中的特定特征反应最好。在这里,我们讨论了最近的进展,确定不同的RGC亚型路由视觉信息在大脑中,包括它们连接到哪些目标,以及它们在这些目标内的组织如何影响视觉处理。我们还强调了在特定RGC亚型之间建立因果联系的例子,它们的中央连接图和光介导行为的定义方面,我们建议使用能够将这些分析扩展到视觉感知电路的技术。
Everything the brain knows about the content of the visual world is built from the spiking activity of retinal ganglion cells (RGCs). As the output neurons of the eye, RGCs include ~20 different subtypes, each responding best to a specific feature in the visual scene. Here we discuss recent advances in identifying where different RGC subtypes route visual information in the brain, including which targets they connect to and how their organization within those targets influences visual processing. We also highlight examples where causal links have been established between specific RGC subtypes, their maps of central connections and defined aspects of light-mediated behavior and we suggest the use of techniques that stand to extend these sorts of analyses to circuits underlying visual perception.
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