Self-organization of plasticity and specialization in a primitively social insect.
Self-organization of plasticity and specialization in a primitively social insect.
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DOI：
10.1016/j.cels.2022.08.002
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发表时间：
2022-09-21
期刊：
影响因子：
9.3
通讯作者：
中科院分区：
文献类型：
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生物系统不仅有能力建立和牢固地维持复杂的结构，而且有能力迅速破坏和重建这些结构。在这里，我们使用Polistes黄蜂的原始社会，我们表明强大的专业化和快速可塑性都是多尺度动力学的涌现特性。我们将理论与实验结合起来，在通过移除蚁后扰乱了社会结构之后，将时间分辨的多组学与视频记录相关联。研究表明，蜂王-工蜂二态性依赖于所有昆虫中分子蜂王表型的发育和通过不对称相互作用抑制这种表型的群体规模之间的平衡。这使得Polistes在面对分子状态的内在扰动时保持稳定，同时对影响整个社会的外在线索做出可塑性反应。动态DNA甲基化强化了社会结构的长期稳定性。我们的研究提供了在生物系统中如何实现专业化和可塑性的一般原则。本文的透明同行评议过程记录包含在补充信息中。实验和理论揭示了Polistes黄蜂是如何实现专业化和可塑性的，蜂王表型的分子上调是通过群体规模的抑制来平衡的，这使得Polistes黄蜂能够区分内在和外在的扰动。Patalano等人表明，原始社会黄蜂的强大专门化和快速可塑性源于分子后表型的发展及其群体规模抑制之间的自组织平衡。这使得Polistes在面对内部分子扰动时保持稳定，同时对外部线索做出可塑性反应。
Biological systems have the capacity to not only build and robustly maintain complex structures but also to rapidly break up and rebuild such structures. Here, using primitive societies of Polistes wasps, we show that both robust specialization and rapid plasticity are emergent properties of multi-scale dynamics. We combine theory with experiments that, after perturbing the social structure by removing the queen, correlate time-resolved multi-omics with video recordings. We show that the queen-worker dimorphism relies on the balance between the development of a molecular queen phenotype in all insects and colony-scale inhibition of this phenotype via asymmetric interactions. This allows Polistes to be stable against intrinsic perturbations of molecular states while reacting plastically to extrinsic cues affecting the whole society. Long-term stability of the social structure is reinforced by dynamic DNA methylation. Our study provides a general principle of how both specialization and plasticity can be achieved in biological systems. A record of this paper’s transparent peer review process is included in the supplemental information. Experiments and theory reveal how Polistes wasps achieve specialization and plasticity Molecular upregulation of queen phenotype is balanced by colony-scale repression This allows Polistes to distinguish between intrinsic and extrinsic perturbations Combining theory with experiments, Patalano et al. show that both robust specialization and rapid plasticity in primitive social wasps result from a self-organized balance between the development of a molecular queen phenotype and its colony-scale inhibition. This allows Polistes to be stable against intrinsic molecular perturbations while reacting plastically to extrinsic cues.
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影响因子：
3.3
作者：
Jeong H;Wu X;Smith B;Yi SV
通讯作者：
Yi SV
DOI：
10.1073/pnas.1818759116
发表时间：
2019-02-26
影响因子：
11.1
作者：
Ocko, Samuel A.;Heyde, Alexander;Mahadevan, L.
通讯作者：
Mahadevan, L.
影响因子：
3
作者：
Oi, Cintia A.;Oliveira, Ricardo C.;Wenseleers, Tom
通讯作者：
Wenseleers, Tom
影响因子：
3.7
作者：
Hunt JH;Wolschin F;Henshaw MT;Newman TC;Toth AL;Amdam GV
通讯作者：
Amdam GV
影响因子：
21.8
作者：
通讯作者：
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