The economic impact of pandemic influenza in the United States: priorities for intervention.

The economic impact of pandemic influenza in the United States: priorities for intervention.
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DOI:
10.3201/eid0505.990507
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发表时间:
1999-09
影响因子:
11.8
通讯作者:
Fukuda K
Fukuda K
中科院分区:
医学2区
文献类型:
--
作者:
Meltzer MI;Cox NJ;Fukuda K

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我们估计了美国下一次流感大流行的可能影响,并分析了基于疫苗的干预措施的经济影响。使用死亡率,住院数据和门诊就诊,我们估计有89,000至207,000人死亡; 314,000至734,000人住院; 1800至4200万门诊就诊; 2000至4700万额外疾病。高风险患者(占人口的15%)将占所有死亡的约84%。估计经济影响为713亿至1665亿美元,不包括对商业和社会的破坏。如果所有年龄组的人都接种疫苗,每名疫苗接种者将节省21美元。在每名疫苗接种者62美元和25%的总发病率下,我们预计,如果并发症风险不高的人接种疫苗,将造成净损失。为60%的人口接种疫苗将产生最高的经济回报,但在疫苗有效性所需的时间内可能无法实现,特别是如果需要两剂疫苗的话。
We estimated the possible effects of the next influenza pandemic in the United States and analyzed the economic impact of vaccine-based interventions. Using death rates, hospitalization data, and outpatient visits, we estimated 89,000 to 207,000 deaths; 314,000 to 734,000 hospitalizations; 18 to 42 million outpatient visits; and 20 to 47 million additional illnesses. Patients at high risk (15% of the population) would account for approximately 84% of all deaths. The estimated economic impact would be US$71.3 to $166.5 billion, excluding disruptions to commerce and society. At $21 per vaccinee, we project a net savings to society if persons in all age groups are vaccinated. At $62 per vaccinee and at gross attack rates of 25%, we project net losses if persons not at high risk for complications are vaccinated. Vaccinating 60% of the population would generate the highest economic returns but may not be possible within the time required for vaccine effectiveness, especially if two doses of vaccine are required.
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发表时间: 1997-05-01
影响因子: 3.2
作者:
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